Driving energy flow throughout chemical networks By Ludovic Jullien (ENS chimie et UPMC) May 31, 2016 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Envisioned as organized matter, any living system necessarily exists in a dissipative non-equilibrium state. Otherwise it would reduce to immutably stable combinatorial mixtures of chemical compounds....

internal seminar By Aurélien Bour, Florence Bansept, Jonathan Lee Tin Wah May 24, 2016 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 -

AG du labo By - May 24, 2016 at 10:00AM - Salle de séminaires 5ème étage, Tour 32-33 -

Inferring interaction partners from protein sequences By Anne-Florence Bitbol May 10, 2016 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Specific protein-protein interactions play crucial roles in the stability of multi-protein complexes and in signal transduction. Thus, mapping these interactions is key to a systems-level ...

Interactions between DNA repair pathways and CRISPR-Cas systems in Bacteria By David Bikard May 3, 2016 at 11:00AM - Interactions between DNA repair pathways and CRISPR-Cas systems in Bacteria CRISPR-Cas systems confer bacteria and archaea an adaptive immunity against phages and other invading mobile genetic elements. In type II CRISPR-Cas systems, the Cas9 protein introduces double strand ...

Quantitative principles of genome evolution revealed by ancestral genome reconstruction By Gilles Fischer (UPMC) April 12, 2016 at 11:00AM - Quantitative principles of genome evolution revealed by ancestral genome reconstruction Comparative genomics is a powerful approach to understand genome evolutionacross species. The study of synteny conservation between multiple speciesallowed critical conceptual advances on how genomes ...

Addressing the functionality of adaptation in Chemotaxis By Jérôme Wong Ng April 5, 2016 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 A notable feature of bacterial chemotaxis is adaptation : after the application of a step stimulus, the bacterial running time relaxes to its pre-stimulus level. The response to the amino acid ...

Cortical bases of temporal asymmetries in auditory perception. By Brice Bathellier March 29, 2016 at 11:00AM - seminar room (LJP, tower 32-33, 5th floor) "Sound recognition relies not only on spectral but also on temporal cues as evidenced by the profound perceptual impact of time-reversion on common sounds. To address the coding principles underlying ...

Application des lipides microbiens à l'étude des milieux naturels By Arnaud Huguet (UPMC, Laboratoire Milieux environnementaux, transferts et interactions dans les hydrosystèmes et les sols) March 22, 2016 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Les lipides membranaires d’origine microbienne peuvent permettre de mieux comprendre le fonctionnement hydrogéochimique des écosystèmes terrestres et aquatiques. Les ...

Engineering synthetic developmental patterns: how many ways can you make a stripe? By Mark Isalan (Imperial College, London) March 15, 2016 at 10:00AM - Salle de séminaires 5ème étage, Tour 32-33 Synthetic biology is a promising tool to study the function and properties of gene regulatory networks. Gene circuits with predefined behaviors have been successfully built and modeled, but largely on...

Cell-free transcription-translation: from gene circuits to self-assembly in a test tube By Vincent Noireaux (University of Minnesota) March 7, 2016 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Originally developed to decipher the genetic code and study gene regulation, cell-free transcription-translation (TX-TL) systems are becoming powerful platforms to construct biological systems in ...

Centrosome positioning at the cell center, is it that simple? By Manuel Théry (IUH, Hopital Saint-Louis, Paris) February 16, 2016 at 11:00AM - seminar room LJP, tower 32-33, 5th floor During this seminar I will present the current models of centrosome positioning based on pulling and/or pushing forces produced on microtubules. Then, showing experimental data and numerical ...

From gel reinforcement to gel adhesion By Alba Marcellan (Université Pierre et Marie Curie, Laboratoire Sciences et Ingénierie de la Matière Molle, ESPCI ParisTech) February 9, 2016 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Polymer hydrogels can be viewed as containers of solvent, e.g. water, made of a cross-linked network of polymer chains. Gels are interesting objects which combine both liquid-like and solid-like ...

Non-linear optical techniques for biology: applications and developments By Aymeric Leray (Laboratoire Carnot, Université de Bourgogne) February 2, 2016 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Non-linear optical techniques are increasingly used for investigating biological phenomena. These techniques allow ultra-deep imaging in tissues with low photo-toxicity. In this talk, I will first ...

Benchmarking inverse statistical approaches for protein structure and design with lattice-protein models By Rémi Monasson (Laboratoire de physique théorique, ENS Paris) January 26, 2016 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Inverse statistical approaches, modeling pairwise correlations betweenamino acids in the sequences of similar proteins across many differentorganisms, can successfully extract protein structure ...

Flock on a Chip By Denis Bartolo (ENS Lyon, Dept de physique) January 19, 2016 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 I will show how to motorize colloidal particles capable of sensing the orientation of their neighbors and how to handle them in microfluidic chips. These populations of colloidal rollers display ...

Self-organization of rivers and drainage networks By Olivier Devauchelle (Institut de Physique du Globe de Paris) January 12, 2016 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Alluvial rivers build their own bed with the sediment they transport. Asthey do so, they spontaneously select their size and shape, and organizethemselves into beautifully ramified networks. Despite ...

AG du LJP By Membres du LJP January 5, 2016 at 10:00AM - Salle de séminaires 5ème étage, Tour 32-33 -

Perception des écoulements et des vibrations chez la larve de poisson-zèbre : étude comportementale et imagerie (PhD d By Raphaël Olive (LJP) December 15, 2015 at 02:00PM - Salle de l'UFR 927 - Batiment B - 1er étage -salle B120.   Cette thèse de doctorat rend compte du travail réalisé pendant trois ans au sein de l'équipe Imagerie calcique et comportement de la larve de poisson-zèbre ...

Toward microscopic simulations of the cellular environment By Fabio Sterpone (IBPC, Laboratoire de Biochimie Théorique, Paris) December 8, 2015 at 10:00AM - Salle de séminaires 5ème étage, Tour 32-33 Proteins work in an extremely heterogeneous and crowded environment. Indeed 5 to 40 % of the intracellular total volume is occupied by large biomolecules [1]. This crowding condition affects both the ...

The mechanics of bacterial microcolonies By Nicolas Desprat (Laboratoire de physique statistique, ENS, Paris) December 1, 2015 at 10:00AM - Salle de séminaires 5ème étage, Tour 32-33 To colonize surfaces, bacteria must adhere and proliferate. How those terms compete to shape the foundations of biofilm formation is barely understood. When bacteria grow between a coverslip and a gel...

Physical limit to concentration sensing in a background of competing ligands By Thierry Mora (Laboratoire de Physique Statistique, ENS Paris) November 24, 2015 at 10:00AM - Salle de séminaires 5ème étage, Tour 32-33  Many biological objects, such as transmembrane receptors orgene promoters, sense concentrations of chemical entities by bindingthem specifically. However, in many situations, competing ligands ...

Hierarchical self-assembly of colloidal membranes By Thomas Gibaud (ENS Lyon) November 16, 2015 at 11:00AM - Salle de séminaires 5ème étagé, Tour 32-33 Nature excels at building complex functional materials. We however are far from understanding thestructure and mechanism involved in those materials and even further from being able to ...

AG du labo By - November 3, 2015 at 10:00AM - seminar room LJP (tower 32-33, 5th floor) -

LJP Scientific day By Membres du LJP October 8, 2015 at 09:30AM - Salle de l'UFR de physique Les permanenet du LJP présenteront leurs sujets de recherche.

All-optical readout and manipulation of neuronal activity by optical wave front shaping By Valentina Emiliani (Neurophotonics Laboratory, University Paris Descartes) September 28, 2015 at 02:00PM - seminar room LJP, tower 32-33, 5th floor  The ability to perturb and manipulate the flow of excitation and inhibition, enabled by a rapidly developing repertoire of optogenetic actuators, is essential for elucidating causal ...

Speedseminar By Jonathan Lee Tin Wah (DNA/RNA); Javier Pastenes (Langue artificielle); Jean Ollion (Bactéries); Alexis Dubreuil (Poisson) September 21, 2015 at 11:00AM - Seminar room (5th floor, tower 32-33) -

Reconstructing rodent and human Oriented Neuronal Networks to model Neurodegenerative syndroms By Jean-Michel Peyrin September 14, 2015 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 The brain is a complex structure comprising many different neuron populations making specific and long ranged polarized connections, or synapses.As such, neurons are ordered in exquisitely complex yet...

Lighting up proteins in living systems By Arnaud Gautier (ENS, Dept. de Chimie, Paris) June 29, 2015 at 11:00AM - Salle de séminaires 5ème étagé, Tour 32-33   Deciphering the complex mechanisms controlling cells and organisms requires effective imaging systems and fluorescent probes to observe biomolecules in real time with high spatiotemporal...

Oxydation de membranes biomimétiques By Aurélien Bour June 15, 2015 at 11:00AM - Seminar room (tower 32-33, 5th floor) La cardiolipine est un lipide membranaire très abondant dans les tissus subissant un fort stress mécanique ou oxydant. Nous étudions son rôle dans la résistance des ...

A sensory motor loop interfacing the cerebrospinal fluid to central pattern generators in the zebrafish spinal cord By Claire Wyart June 1, 2015 at 02:00PM - Seminar room (tower 32-33, 5th floor) -

Review: Super-resolution optical microscopy By Sergei Kruglik May 18, 2015 at 11:00AM - Seminar room (tour 32-33, 5th floor) -

Simple self-replicators: growth via self-assembly and fissioning via bursting bubbles By Damien Woods (Caltech) April 13, 2015 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) We explore the principles of and experimentally demonstrate an autonomousand natural scheme for molecular self-replication. The talk will discuss a design for a simple DNA self-replicator that in ...

A blueprint for actomyosin assembly and disassembly during pulsed contractions: imaging single molecules in a developing emb By François Robin (Institut de Biologie Paris-Seine) March 30, 2015 at 11:00AM - seminar room LJP (tower 32, 5th floor) Actomyosin-based pulsed contractions are a widespread and highly dynamic form of self-organized contractility that underlies numerous morphogenetic events during early development. However the ...

Efficient coding in recurrent networks By Sopie Deneve (Group for Neural Theory, LNC, DEC, ENS) March 23, 2015 at 11:00AM - Efficient coding in recurrent networks Cortical responses are hugely variable and heterogeneous. Moreover, the brain is amazingly robust, able to withstand lesions and neural deaths with minimal impact on behavior.  But does that ...

The biophysical basis of morphogenesis: symmetry breaking and elongated forms in plants and fungi By Arezki Boudaoud (ENS Lyon) March 16, 2015 at 11:00AM - Seminar room LJP (Tower 32-33, 5ème étage) Despite extensive research, we are far from a comprehensive answer to the question of how cells and organisms adopt well-defined shapes. We addressed this question in the context ...

- By Lucile Julien, LKB, Professeur émérite à l'UPMC March 9, 2015 at 11:00AM - - -

IN VITRO STUDY OF LEUKOCYTES RECRUITMENT EVENTS By Olivier Théodoly February 16, 2015 at 11:00AM - seminar room LJP (5-31) During the immunological response, circulating leukocytes are recruited from the blood system towards inflammatory zones via a complex cascade of events: after exiting the capillary bed, leukocytes ...

-DISCO: How the UVs change my life By Mathieu Refregiers, Synchrotron Soleil February 9, 2015 at 11:00AM - seminar room LJP (5-31) -

Intrinsic and extrinsic determinants of axon growth and lamination in retinal ganglion cells By Filippo Del Bene February 2, 2015 at 11:00AM - seminar room LJP (5-31) Retina Ganglion Cells axons project from the eye to the contralateral optic tectum. We will present data illustrating the importance of axonal transport to regulate axon growth via an ...

Mécano-sensibilité des cellules vivantes: rôle de la rigidité de l'environnement sur la migration cellulaire. By Benoit Ladoux January 19, 2015 at 11:00AM - seminar room LJP (5-31) Les forces mécaniques jouent un rôle important dans la croissance et la formation des tissus et des organes qui composent notre corps. La perception qu'ont les cellules vivantes de ...

Vieillissement, relaxation de contrainte et fracture des hydrogels de biopolymère By Olivier Ronsin January 12, 2015 at 11:00AM - seminar room LJP (5-31) Les hydrogels de biopolymère, matériaux constitués d'un réseau de chaînes de polymères réticulées, gonflé par un solvant aqueux, suscitent...

Raman Tweezers Microspectroscopy of Extracellular Vesicles in ~100 nm Range By Serguei Kruglik December 1, 2014 at 11:00AM - Salle de réunion du LJP (5-31)  In recent years, the existence of a specific way of cell communication based on the release of membranous nano/micro-sized vesicles has been discovered and acknowledged; and the research in ...

Experimental study of metabolic adaptation in time-structure environments. By Jean-Baptiste Boulé November 24, 2014 at 11:00AM - seminar room LJP (tower 32, 5th floor) Life is a history-driven process, pervaded by memories at many scale, from the molecular assembly patterns inside a cell up to the cultural organization of human societies. Memory can be defined as a ...

Multi-protein complexes: functions and constraints By Anne-Florence Bitbol (Princeton University) November 21, 2014 at 11:00AM - seminar room LJP (tower 32, 5th floor) (Lewis-Sigler Institute for Integrative Genomics and Department of Physics, Princeton University) Self-assembled multi-protein complexes play key roles in cells, e.g., as molecular motors, enzymes, ...

Time-gated detection of near infrared quantum for in vivo cell tracking in small animals By Sophie Bouccara (ESPCI) November 3, 2014 at 11:00AM - seminar room LJP (tower 32, 5th floor) In vivo cell tracking is a promising tool to improve our understanding of certainbiological processes (circulating tumour cells migration, immune cells activity).Fluorescence microscopy ensures a high...

Slow fronts at the transition from static to kinetic friction By Julien Scheibert - Laboratoire de Tribologie et Dynamique des Systèmes, CNRS / Ecole Centrale de Lyon, Ecully October 28, 2014 at 11:00AM - Salle de réunion du LJP The contact between macroscopic rough solids is made of many micrometric asperities in contact. Under increasing shear force, a catastrophic rupture of the interface can occur through the ...

Biomimetism of rats tactile perception By Laure Nayélie Claverie (LJP) October 27, 2014 at 11:00AM - seminar room (tower 32, 5th floor) Nous nous intéressons aux mécanismes de transduction de l'information tactile chez le rat qui utilise ses moustaches faciales ou vibrisses pour appréhender son environnement. Nous...

Seeing bacteria grow - from single molecules to cell shape and size By Sven van Teeffelen (Pasteur Institute) October 20, 2014 at 11:00AM - seminar room LJP (tower 32, 5th floor) Bacterial cell shape is important for cell viability and many biological functions such as motility, host invasion, and biofilm formation. Rod-like Gram-negative bacteria such as Escherichia coli ...

Learning from fluctuations: The mechanics of active and passive cellular assemblies By Timo Betz (Institut Curie, CNRS) October 13, 2014 at 11:00AM - seminar room LJP (tower 23, 5th floor) Understanding the intriguing complexity of living systems is one of the main driving forces of science. To gain insight we use biomimetic systems that reconstitute well defined cellular assemblies and...