TBA By Andrea Cairoli (Crick Institute London) June 14, 2022 at 12:00AM - Salle de séminaires 5ème étage - LJP - Tour 32-33 TBA

TBA By Lorraine Montel (LJP, Sorbonne Université) June 7, 2022 at 11:00AM - Salle de séminaires 5ème étage - LJP - Tours 32-33 TBA

Filamentous bacteriophages: versatile model building blocks in soft matter and biomaterials By Eric Grelet (CRPP Bordeaux) May 17, 2022 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Filamentous bacteriophages with their features like outstanding monodispersity and their ability to self-organize into a myriad of ordered structures motivate the strong interest they have raised as ...

Choreographing the dance of active nematic defects By Teresa Lopez-Leon (ESPCI Paris) April 12, 2022 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Active nematics are biomimetic liquid crystals in which a 2D network of microtubule filaments is set in motion by the action of molecular motors (1, 2). In its steady state, this system usually ...

Coupled stochastic dynamics and kinetics simulations with applications to Biology and Chemistry By Marina Katava (IBPC, Paris) April 5, 2022 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Complex systems can be successfully modeled in computer simulations. Due to the high computational cost of the numerical algorithms, different techniques are adapted to suit particular time- and ...

Physics of mammalian blastocyst morphogenesis By Jean-Léon Maître (Institut Curie, Paris) and Hervé Turlier (Collège de France, Paris) March 29, 2022 at 11:00AM - Salle de séminaires 5ème étage - LJP - Tour 32-33 The formation of the blastocyst during preimplantation development constitutes a unique opportunity to study living mammalian embryos. The blastocyst consists of a surface epithelium enveloping a ...

Control of biological processes By Efe Ilker (Max Planck Institute for the Physics of Complex Systems, Dresden) March 22, 2022 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Time is a major constraint for life. Biological systems need to adapt and respond accurately to the changes in their environment. Having fine-grained control in nonequilibrium processes via external ...

Context-dependent selectivity to natural scenes in the retina By Ulisse Ferrari and Olivier Marre (Institut de la Vision, Paris) March 15, 2022 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Retina ganglion cells extract specific features from natural scenes and send this information to the brain. In particular, they respond to local light increase (ON responses), and/or decrease (OFF). ...

TBA By Internal seminar March 8, 2022 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 TBA

Active mechanical and electrohydraulic properties of tissues By Charlie Duclut (MSC, Université de Paris) February 22, 2022 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Tissues are assemblies of large numbers of cells, which form a soft active material. Their dynamics are governed by chemical signals between cells, which both coordinate active mechanical processes ...

internal seminar By internal seminar January 18, 2022 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 internal seminar

Statistical mechanics for the analysis of immunogenic motives in SARS-COv2 sequences and beyond By Simona Cocco (LPENS Paris) January 11, 2022 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 When a virus enters a new host, it can present pathogen-associated molecular patterns (PAMPs) that are rarely seen in circulating strains that have adapted to that host’s immune environment over...

HDR : Mechanical properties of tissues and mechanosensitivy : a biomimetic approach By Lea-Laëtita Pontani December 14, 2021 at 02:00PM - LJP seminar room, 5th floor, corridor 32-33 HDR

A multiscale chemotaxis assay to unravel how motile bacteria navigate their environment(s) By Marianne Grognot (ESPCI Paris) December 8, 2021 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Flagellated bacteria swim by rotating one or several flagella; motility alone results in a random walk, but the flagella’s rotation can be influenced by an intracellular sensory system that ...

Spontaneous propulsion of an isotropic colloid in a phase-separating environment By Pierre Illien (Sorbonne U) December 7, 2021 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 The motion of active colloids is generally achieved through their anisotropy, as exemplified by Janus colloids. Recently, there was a growing interest in the propulsion of isotropic colloids, ...

Buckling and curling of epithelial monolayers By Jonathan Fouchard (IBPS) November 30, 2021 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Epithelial monolayers are soft thin sheets which shape the body and organs of many multi-cellular organisms. Competition between stretching and bending characterizes shape transitions of thin elastic ...

Seasonal influenza viruses: Limited predictability of evolution & Inference of reassortment networks By Pierre Barrat-Charlaix (Univ. Basel) November 23, 2021 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Seasonal influenza viruses repeatedly infect humans in part because they rapidly change their antigenic properties and evade host immune responses, necessitating frequent updates of the vaccine ...

Making and Folding Colloidomers By Jasna Brujic (NYU) November 9, 2021 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Making and Folding Colloidomers By Design Angus McMullen, Maitane Munoz Basagoiti, Zorana Zeravcic, Jasna Brujic Protein folding is an efficient mechanism used by biology to make molecules with a ...

internal seminar By Nicolas Escoubet & Nabil-Bey Baroudi October 19, 2021 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 internal seminar

Internal Seminar By Yuliia Vyborna / Natalia Belén Beiza Canelo May 18, 2021 at 04:00PM - Salle de séminaires 5ème étage, Tour 32-33 TBA

Motility regulation of run-and-tumble bacteria: from directed to self-organization By Julien Tailleur April 13, 2021 at 04:00PM - Salle de séminaires 5ème étage, Tour 32-33 Equilibrium statistical mechanics tells us how to control the self-assembly of passive materials by tuning the competition between energy and entropy to achieve desired states of organization. Out of ...

Deconstructing human nervous system development in health and disease : an embryoid and organoid perspective By Stéphane Nedelec (IFM) April 6, 2021 at 04:00PM - Salle de séminaires 5ème étage, Tour 32-33 Our lab is studying the molecular and cellular basis of human nervous system development in health and disease. We seek to decode the principles controlling the specification and organization of ...

Internal seminar By Darka Labavic / Julie Lafaye March 16, 2021 at 04:00PM - Salle de séminaires 5ème étage, Tour 32-33 TBA

Mesodermal growth and morphogenesis in chicken embryos By Karine Guevorkian (Institut Curie) March 9, 2021 at 04:00PM - Salle de séminaires 5ème étage, Tour 32-33 The life of an embryo starts as a ball of undifferentiated cells. Gradually, biochemical signals, in concert with mechanical cues, pattern the embryonic tissues from which organs emerge. Understanding...

Modelling Immune Recognition with Restricted Boltzmann Machines By Barbara Bravi (LPENS) December 15, 2020 at 04:00PM - Zoom The immune response of an organism when it is infected by a pathogen is based on the recognition of small portions of its proteins. This raises two questions: what protein portions are relevant to ...

Chirality and non-reciprocal interactions: Creating new liquid crystals from activity By Ananyo Maitra (Laboratoire Jean Perrin) December 8, 2020 at 03:00PM - Zoom Active matter theories generally augment descriptions of passive liquid crystals with nonequilibrium forces and currents, thereby addressing how activity affects these structures. In this talk, I will...

Understanding the mechanics of coordinated tissue movements in zebrafish gastrulation By Silvia Grigolon (Laboratoire Jean Perrin) December 1, 2020 at 04:00PM - Zoom Embryo morphogenesis relies on highly coordinated movements of different tissues as well as cell differentiation and patterning. However, remarkably little is known about how tissues coordinate their ...

Spatio-temporal patterning of living cells with extracellular DNA programs By Marc Van Der Hofstadt (Laboratoire Jean Perrin) November 24, 2020 at 11:00AM - Zoom The microenvironment surrounding eukaryotic cells in complex organisms is constantly evolving. Its out-of-equilibrium behaviour is due to the perpetual production and degradation of its constituents ...

Eukaryotic cells as interacting living particles By Joseph d’Alessandro (Institut Jacques Monod, Paris) November 17, 2020 at 11:00AM - Zoom Cells move. They propel themselves using an internal machinery which endows them with the characteristics of active particles. At the same time, they interact dynamically with their environment and ...

Fluid pumping, lumen nucleation and electro-hydraulic phenomena in cell assemblies By Charlie Duclut (Max Planck, Dresden) November 10, 2020 at 11:00AM - Zoom In addition to generating forces and reacting to mechanical cues, cell assemblies and tissues are characterized by their capacity to actively pump fluid, thanks to active ion transport. By pumping ...

Single-molecule analysis of multicomponent DNA repair pathways By Terence Strick (ENS) March 10, 2020 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 DNA repair is typically a multi-step, multi-component process in which proteins detect a DNA lesion; confirm the presence of the lesion; excise the lesion; and replace the excised DNA with ...

Internal Seminar By Hugo Trentesaux / Aurore Woller March 3, 2020 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 TBA

Linking lineage and population observables in growing cell populations By David Lacoste (ESPCI) February 25, 2020 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 The question of how a cell controls its size is an one, which despite decades of research is still timely because the old experiments have been unable to measure the heterogeneity of cell populations ...

Microfabricated tools to study embryonic patterning in vitro By Benoît Sorre (MSC) February 4, 2020 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 One of the most striking features of embryonic development is that differentiation is happening in a spatially ordered fashion: tissue self-organize to form well-defined patterns that pre-figure the ...

Natural selection of compartmentalized autocatalytic chemical reactions By Philippe Nghe (ESPCI) January 21, 2020 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Natural selection, the differential reproduction and survival (differential fitness) of individuals due to differences in phenotype, is an essential component of evolution in biological systems. ...

Emerging order, from crystals of colloids to fish schools By Sophie Ramananarivo (LadHyX Polytechnique) January 7, 2020 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Living systems constantly exploit active fluctuations in their processes, to boost transport or assist assembly. Self-propelled colloids, that consume energy to move hold the same potential for ...

Modelling and predicting antigen presentation with Restricted Boltzmann Machines By Barbara Bravi (ENS) December 17, 2019 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Immune recognition of infected and malignant cells requires presentation on their surface of antigens (i.e. short peptides) by human leukocyte antigen class I (HLA-I) proteins, which are coded by one ...

Soft Matter for the Origin of Life: Liquid Crystals, Phase Transitions and the Prebiotic Emergence of Biopolymers By Tommaso P. Fraccia (IPGG - ESPCI) December 12, 2019 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 The abiotic formation of biopolymers from their monomeric building blocks and the emergence of cellular structures are still unsolved problems in the origin of life investigation. In this frame soft ...

Retinal computations and circuits integrating contextual information By Olivier Marre (Institut de la vision) December 10, 2019 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 At the retinal output, a common assumption is that ganglion cells of a single type extract a single stimulus feature from the visual scene to form a feature map. Yet they can also respond to very ...

Can a population targeted by an artificial gene drive be rescued? By Florence Débarre (Sorbonne Université) December 3, 2019 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Gene drive, a type of genetic control, consists in using selfish genetic elements to modify or eradicate populations. The idea is not new, but has only recently become feasible, thanks to the ...

Cytoskeletal crosstalk during cell migration By Sandrine Etienne-Manneville (Pasteur) November 26, 2019 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Cell migration requires a dramatic and coordinated reorganization of the different elements of the cytoplasmic cytoskeleton, composed of three types of filamentous structures: actin microfilaments, ...

Deep learning driven model discovery in biology and physics By Remy Kusters (CRI) November 19, 2019 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 As scientific data sets become richer and increasingly complex, machine learning (ML) tools become more useful and widely applied. Discovering a mechanistic model, rather than predicting the outcome ...

Formation and functionalization of cellular lipid droplets By Abdou Rachid Thiam (ENS) November 12, 2019 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 A key feature of cell survival is the ability to synchronously respond to environmental energy fluctuations. Excess energy is stored by cells in neutral lipid oil forms such as triglycerides and ...

Nonlinear dynamics of chemically active microdrops grants an insight into interfacial chemistry By Matvey Morozov (Université Libre de Bruxelles) November 4, 2019 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 A chemically active microdrop that is suspended in the bulk of a reagent solution is an example of a non-equilibrium physicochemical system akin to cells and vesicles. Owing to their non-equilibrium ...

Superinfection and cure of infected cells as mechanisms for hepatitis C virus adaptation and persistence By Ruian Ke (Los Alamos) October 18, 2019 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 RNA viruses exist as a genetically diverse quasispecies with extraordinary ability to adapt to abrupt changes in the host environment. However, the molecular mechanisms that contribute to their rapid ...

Perception de la texture en bouche : une approche biomimétique By Jean-Baptiste Thomazo October 8, 2019 at 02:00PM - Amphithéâtre Durand Le système langue-palais est capable de détecter de fines variations de texture en bouche là où le meilleur des rhéomètres est essentiellement aveugle. Une ...

The mechanobiology of vascular colonization by Neisseria meningitidis By Daria Bonazzi (Pasteur) October 8, 2019 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) During human meningococcal infections, bacteria adhere to the endothelium, accumulate in the form of aggregates and finally fill up blood vessels, causing severe diseases such as septicemia and ...

Spontaneous shape transitions of active matter By Anne Bernheim-Groswasser (Ben Gurion University) October 4, 2019 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) Shape transitions in developing organisms can be driven by active stresses, notably, active contractility generated by myosin motors. The mechanisms generating tissue folding are typically studied in ...

Sinister Self-Assembly - Colloidal Architecture Using DNA Origami By Matan Ben Zion (ESPCI) October 1, 2019 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) Self-assembly and self-organization are two big challenges in natural sciences. What are the rules governing the emergence of greater structures from unassuming individuals? Does statistical ...

Internal Seminar By Shunichi Kashida/Guillaume Le Goc September 24, 2019 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) TBA