Dynamics and mechanical properties of actin cytoskeleton networks in vitro and in cellulo By Olivia du Roure (ESPCI) February 13, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Actin is a protein which self-assembles into highly dynamic semi-flexible filaments organized, within the cells, in different kind of meshworks (bundles, crosslinked or dendritic networks). The ...

TBA By Loïc Marrec and Marc Van Der Hofstadt Serrano (LJP, Internal seminar) February 6, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Loïc's talk Quantifying the impact of a periodic presence of antimicrobial on resistance evolution in ahomogeneous microbial population of fixed sizeAbstract:Antimicrobial resistance is a major ...

Hydrodynamics of bacteria By Eric Lauga (Cambridge, UK) January 30, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Most motile bacteria are equipped with multiple helical flagella, slender appendages whose rotation in viscous fluids allow the cells to self-propel. We highlight in this talk three consequences of ...

Cybergenetics : control of gene expression and biological circuits By Pascal Hersen (MSC, Paris Diderot et CNRS) January 23, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Gene expression plays a central role in the orchestration of cellular processes. We recently developed an experimental platform for real-time, closed-loop control of gene expression that integrates ...

Disassembly of actin filaments drive actin network contraction in the starfish oocyte By Serge Dmitrieff (EMBL) January 16, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 While contraction of muscle actomyosin assemblies is well understood, this is not the case for disordered networks of actin filaments (F-actin) driving diverse essential processes in animal cells. For...

Vitrimers: Insoluble yet reshapable chemically crosslinked networks By François Tournilhac (ESPCI, Lab. Matière molle et chimie) January 9, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Vitrimers, invented in 2011, are chemically crosslinked networks characterized by the presence of exchangeable links, a feature that allows to change topology while keeping the integrity of the ...

Causal Inference in Cognitive Neuroscience By Moritz Grosse-Wentrup (Max Planck Tuebingen) December 12, 2017 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Neuroimaging techniques enable us to establish associations betweenbrain activity and cognitive functions. Associations do not inform us,however, about the causal mechanisms that govern how brain ...

New autocatalytic reaction schemes for molecular amplification in biomolecular diagnostics. By François Mavré (Lab. Electrochimie Moléculaire, Université Paris Diderot) December 5, 2017 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Biomolecular diagnostic requires high level of selectivity and sensitivity to provide relevant information about the pathological state of a patient. While selectivity relies often on specific ...

Secondary structure of DNA: Epigenetic regulation and resolution by helicases By Phong Lan Thao TRAN (Regulation et Dynamique des Genomes, Muséum) November 28, 2017 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Guanine quadruplexes (G4) are non-canonical four-stranded nucleic acid structures formed by guanine-rich DNA and RNA sequences. G4 motifs, which are commonly found in gene promoters, replication ...

Faire des choix chez l'amibe sociale et le ver C. elegans By Jean-Marc Di Meglio (Matière et Systèmes Complexes - Université Paris Diderot et CNRS) November 21, 2017 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Nous présentons des expériences où des animaux modèles sont confrontés à une prise de décision : nager ou ramper chez le ver nématode, se ...

Confining and releasing cell monolayers By Pascal Silberzan (Institut Curie, Paris) November 14, 2017 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Cell monolayers routinely exhibit collective behaviors largely controlled by cell-cell interactions. In this context, confinement and boundary conditions play an important role in the organization and...

Bacteria Are Stressed Out Too: The Physics of Mechanosensation By Rob Phillips (Caltech, USA) October 24, 2017 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) The control of water flow in living organisms is central to their survival.Amphibians die in long time exposure to salt water raising many biogeographical questions abouthow oceanic islands like those...

Tba By Aristides Arrenberg September 27, 2017 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Tba

Internal seminar: droplet generation and vestibular stimulation By Manon Valet and Geoffrey Migault September 20, 2017 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Manon will speak about "Quasi-static microdroplet production in a capillary trap" Manon's abstract: "We have developed a method to produce aqueous microdroplets in an oil phase, based on the periodic...

Deciphering the family of immune cells at the single cell level By Leïla Périé (Institut Curie) September 13, 2017 at 11:00AM - Salle de réunion LJP (tour 32-33, 5ème étage) How heterogeneous systems of cells constituting multicellular organisms establish, organize and achieve coordination persists as a central question in natural sciences. Whereas stochastic gene or ...

Vulgariser la physique autrement By Julien Bobroff (Laboratoire de Physique des Solides, Université Paris-Sud et CNRS) June 21, 2017 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Vous souvenez-vous du prix Nobel de physique de cette année sur la topologie dans les solides ? Faîtes le test autour de vous : il est passé relativement inaperçu, ...

Biomechanics in plants and fungi: fern sporangium catapult and invasive filamentous fungi growth By Xavier Noblin (Institut de Physique de Nice, U. Nice et CNRS) June 14, 2017 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33   In the first part, I will describe our study on ferns sporangia where negative pressures lower than -100 bar are used in this catapult-like elastic beam.   ...

Optogenetic dissection of cell polarity and migration By Mathieu Coppey (Institut Curie) June 7, 2017 at 11:00AM - Salle de réunion LJP (tour 32-33, 5ème étage) The migration of eukaryotic cells requires a high coordination of molecular activities in space and time. When migrating, cells present a highly polarized state as revealed by the many subcellular ...

Extrinsic mechanical forces mediate retrograde axon extension in a developing neuronal circuit By Marie Breau (Institut de Biologie Paris Seine) May 24, 2017 at 11:00AM - Salle de réunion LJP (tour 32-33, 5ème étage) During neuronal circuit formation, neurons move towards their final location while growing axons towards their target. Whereas the biochemical guidance cues involved in neuronal migration and axon ...

The non-intuitive phenomenology of highly diverse microbial communities By Mikhail Tikhonov (Harvard) May 17, 2017 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 The sequencing-driven revolution in microbial ecology unveiled the complexity of microbial communities that shape the health of our planet, and our own. Despite the ever-growing amount of data, our ...

Vascular colonization by Neisseria meningitidis By Guillaume Duménil (institut Pasteur) May 10, 2017 at 11:00AM - Salle de réunion LJP (tour 32-33, 5ème étage) Bacterial infection of human vasculature can lead to unregulated systemic activation of coagulation and innate immunity and rapidly becomes life threatening. Neisseria meningitidis is a vascular ...

Internal seminar LJP: Stochastic gene expression and hydrogel swelling By Alexandre Deloupy et Thibault Bertrand May 3, 2017 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Alexandre Deloupy: Stochastic gene expression in Bacillus subtilis *** Thibault Bertrand: Dynamics of Swelling and Drying in Hydrogels "Swelling is a fundamental process in biology, engineering, ...

Dendritic and cellular mechanisms of spatial representations in the brain By Christoph Schmidt-Hieber (Institut Pasteur) April 26, 2017 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) How are neuronal codes of the spatial environment generated at thelevel of synapses, neurons, and neuronal circuits? Neurons in layer 2of the medial entorhinal cortex (MEC2) fire spikes at regular ...

Protein phase transitions in and out of cells By Ned Wingreen (Physics Dept., Princeton University, USA) April 18, 2017 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Biologists have recently come to appreciate that eukaryotic cells are home to a multiplicity of non-membrane bound compartments, many of which form and dissolve as needed for the cell to function. ...

Confotronic Machines By Igor Kulic (CNRS, Institut Charles Sadron, Strasbourg) April 5, 2017 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Many biological structures including viral capsids,  transmembrane proteins and filaments (DNA, F-actin , bacterial flagella and microtubules) are well known to undergo conformational ...

Ecological scaffolding and the origins of multicellularity By Paul B Rainey (New Zealand Institute for Advanced Study and ESPCI) March 29, 2017 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 The evolution of multicellular life from unicellular predecessors marks a Major Evolutionary Transition that underpins the emergence of biological complexity.  Cooperation is central to the ...

AG LJP By Jean Perrin March 22, 2017 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 -

Disordered actomyosin contracts in unexpected ways By Martin Lenz (LPTMS of CNRS and Université Paris-Sud) March 15, 2017 at 11:00AM - Disordered actomyosin contracts in unexpected ways The motion of living cells is in large part due to the interaction of semi-flexible actin filaments (F-actin) and myosin molecular motors, which induce the relative sliding of F-actin. It is often ...

Cytoskeletal Mechanics: Contractile Actomyosin Networks By François Nédélec (Cell Biology and Biophysics, EMBL Heidelberg, Germany) March 8, 2017 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 with Julio Belmonte and Maria Leptin The cytoskeleton drives many essential processes in vivo, but for this the system of filaments will arrange itself into different overall spatial organizations, ...

HdR defense of Raphaël Candelier By Raphael Candelier (LJP/UPMC et CNRS) February 21, 2017 at 10:30AM - Charpak amphitheatre Raphaël Candelier is delighted to invite you to his habilitation à diriger des recherches defense that will be held on tuesday, Febreuary 21 at 10:30 AM at the Charpak amphitheatre ...

Cell shape, microtubule asters and early embryonic development By Nicolas Minc (Institut Jacques Monod, U. Paris Diderot) February 1, 2017 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Life for all animals starts with the fertilization of the egg, followed by the centration of the sperm nucleus and a 3D-choreography of reductive cell divisions called cleavage patterns. These ...

Instabilities in Bacterial Biofilms By Carine Douarche (LPS, Université Paris Sud) January 25, 2017 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 When observing the morphogenesis of Bacillus subtilis floating biofilms, we detect some kinds of bacteria self-assemblies at the liquid-air interface that further undergo a bioconvection process. ...

Diversity of immune receptor repertoires By Aleksandra Walczak (LPT, ENS) January 11, 2017 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Recognition of pathogens relies on the diversity of immune receptor proteins. Recent experiments that sequence the entire immune cell repertoires provide a new opportunity for quantitative insight ...

Polarizing tissue morphogenesis by mechanical stress By Michel Labouesse (IBPS, UPMC) January 4, 2017 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 We are using a simple model, the nematode C. elegans, to analyze how mechanical forces influence specific cellular processes and conversely on how tissues withstand forces during morphogenesis. The C....

Journée PCC / LJP By Physico-Chimie Curie et Laboratoire Jean Perrin December 9, 2016 at 09:00AM - TBA -

Environment sensing during bacterial collective motions By Rémy Colin, MPI for terrestrial microbiology, Marburg, Allemagne December 7, 2016 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Flagellated bacteria, such as Escherichia coli, swim by a succession of more or less straight runs and short reorientations, the tumbles. The bacteria probe their environment while swimming through ...

Some physical aspects of single-cell mechanosensing By Atef Asnacios (MSC, Paris Diderot) November 30, 2016 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 As part of their physiological functions, most cells need to adapt to their mechanical environment. In particular, the rigidity of the extracellular matrix was shown to control cell traction forces, ...

AG By - November 18, 2016 at 11:00AM - Salle de réunion du LJP (tour 32-33, 5ème étage) -

Examining prokaryotic community behavior using 3D printing By Aimee K. Wessel (Institut Pasteur) November 16, 2016 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Bacterial communities engage in social activities, exhibiting behaviors such as communicating with small signaling molecules (quorum sensing [QS]) and building antibiotic-resistant biofilms. Most of ...

Mechanosensitivity of junctional beta-catenin: from mesoderm mechanotransductive evolutionary origins to tumorigen By Emmanuel Farge ( Mechanics and Genetics of Embryonic Development group, UMR168, Institut Curie, 11 rue Pierre et Marie Curie 75005 Paris, France.) October 18, 2016 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) Bilaterians are complex organisms, characterized by the existence of a mesoderm tissue from which most of animal complex organs develop. Mesoderm emerged 570 millions years ago from cnidarians that ...

The many faces of emulsions By Léa-Laetitia Pontani (INSP, UPMC) October 11, 2016 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 We use emulsions as a model system for a wide range of applications: from the study of biomimetic tissues to the production of patchy particles for self assembly, or the exploration of granular matter...

Mean first-passage times of non-Markovian random walkers in confinement By Raphael Voituriez (LJP /UPMC) October 4, 2016 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 The first-passage time is a key quantity for evaluating the kinetics of various processes, and in particular chemical reactions involving "small" numbers of particles. A striking example is given by ...

Neural synchrony in early sensory processing By Romain Brette September 27, 2016 at 11:00AM - Seminar room LJP (tour 32-33, 5th floor) What is neural synchrony good for? First, I will show that, whether synchrony has a functional role or not, neurons are extremely sensitive to coincidences among its inputs. To understand the ...

Structures and dynamics of visual and auditory cortex: cortical waves detections By Luc Faubert (Unit of Neuroscience, Information & Complexity, CNRS-FRE 3693, Gif/Yvette) September 20, 2016 at 11:00AM - Seminar room LJP (tour 32-33, 5th floor) -

AG du labo By - September 13, 2016 at 10:30AM - Salle de séminaires 5ème étage, Tour 32-33 -

PhD defence By Laure Claverie July 7, 2016 at 02:00PM - l'amphi Charpak, Patio 22-33. Les rongeurs utilisent leurs vibrisses pour sonder tactilement leur environnement. Tout contact induit des contraintes mécaniques lentes quasi-statiques et rapides vibratoires, qui se propagent...

Multiphoton imaging of developing tissues: multimodal, multicolor and light-sheet approaches By Emmanuel Beaurepaire & Willy Supatto June 28, 2016 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) Modern issues in systems biology require tissue-scale measurements of multiple cell parameters. Multiphoton fluorescence microscopy has proven invaluable for tissue studies with its ability to provide...

Engineering chemical organization using DNA-based reaction networks By Adrian Zambrano June 21, 2016 at 11:00AM - Seminar room LJP, 5th floor We are inspired by the morphogenesis processes that are involved in the emergence of shape and structure in living systems. We aim to engineer chemical and material organization using the two most ...

Novel Multispectral Imaging Technique for the wide field quantification of optical properties By Veronica Sorgato (CEA de Grenoble) June 14, 2016 at 11:00AM - Novel Multispectral Imaging Technique for the wide field quantification of optical properties The Novel Multispectral Imaging Technique that has been developed, intends to aid oral cancer diagnosis by providing quantitative spatial maps of absorption and diffusion properties obtained through ...

Cortex on demand: a disinhibitory circuits of the cerebellar cortex. By Stéphane Dieudonné (IBENS , Paris, France) June 7, 2016 at 11:00AM - Seminar room LJP, 5th floor The cerebellum plays an essential role in coordinating sensori-motor integration and motor execution. In the classical view of the cerebellum, sensory-motor inputs carried by the mossy fibers are ...