Dynamics and mechanical properties of actin cytoskeleton networks in vitro and in cellulo Par Olivia du Roure (ESPCI) Le 13 Février 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Actin is a protein which self-assembles into highly dynamic semi-flexible filaments organized, within the cells, in different kind of meshworks (bundles, crosslinked or dendritic networks). The ...

Evolution of antimicrobial resistance and Synthetic networks with cells Par Loïc Marrec and Marc Van Der Hofstadt Serrano (LJP, Internal seminar) Le 6 Février 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Loïc's talk Quantifying the impact of a periodic presence of antimicrobial on resistance evolution in ahomogeneous microbial population of fixed sizeAbstract:Antimicrobial resistance is a major ...

Hydrodynamics of bacteria Par Eric Lauga (Cambridge, UK) Le 30 Janvier 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Most motile bacteria are equipped with multiple helical flagella, slender appendages whose rotation in viscous fluids allow the cells to self-propel. We highlight in this talk three consequences of ...

Cybergenetics : control of gene expression and biological circuits Par Pascal Hersen (MSC, Paris Diderot et CNRS) Le 23 Janvier 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Gene expression plays a central role in the orchestration of cellular processes. We recently developed an experimental platform for real-time, closed-loop control of gene expression that integrates ...

Disassembly of actin filaments drive actin network contraction in the starfish oocyte Par Serge Dmitrieff (EMBL) Le 16 Janvier 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 While contraction of muscle actomyosin assemblies is well understood, this is not the case for disordered networks of actin filaments (F-actin) driving diverse essential processes in animal cells. For...

Vitrimers: Insoluble yet reshapable chemically crosslinked networks Par François Tournilhac (ESPCI, Lab. Matière molle et chimie) Le 9 Janvier 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Vitrimers, invented in 2011, are chemically crosslinked networks characterized by the presence of exchangeable links, a feature that allows to change topology while keeping the integrity of the ...

Causal Inference in Cognitive Neuroscience Par Moritz Grosse-Wentrup (Max Planck Tuebingen) Le 12 Décembre 2017 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Neuroimaging techniques enable us to establish associations betweenbrain activity and cognitive functions. Associations do not inform us,however, about the causal mechanisms that govern how brain ...

New autocatalytic reaction schemes for molecular amplification in biomolecular diagnostics. Par François Mavré (Lab. Electrochimie Moléculaire, Université Paris Diderot) Le 5 Décembre 2017 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Biomolecular diagnostic requires high level of selectivity and sensitivity to provide relevant information about the pathological state of a patient. While selectivity relies often on specific ...

Secondary structure of DNA: Epigenetic regulation and resolution by helicases Par Phong Lan Thao TRAN (Regulation et Dynamique des Genomes, Muséum) Le 28 Novembre 2017 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Guanine quadruplexes (G4) are non-canonical four-stranded nucleic acid structures formed by guanine-rich DNA and RNA sequences. G4 motifs, which are commonly found in gene promoters, replication ...

Faire des choix chez l'amibe sociale et le ver C. elegans Par Jean-Marc Di Meglio (Matière et Systèmes Complexes - Université Paris Diderot et CNRS) Le 21 Novembre 2017 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Nous présentons des expériences où des animaux modèles sont confrontés à une prise de décision : nager ou ramper chez le ver nématode, se ...

Confining and releasing cell monolayers Par Pascal Silberzan (Institut Curie, Paris) Le 14 Novembre 2017 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Cell monolayers routinely exhibit collective behaviors largely controlled by cell-cell interactions. In this context, confinement and boundary conditions play an important role in the organization and...

Bacteria Are Stressed Out Too: The Physics of Mechanosensation Par Rob Phillips (Caltech, USA) Le 24 Octobre 2017 à 11h00 - Salle de réunion LJP (tour 32-33, 5ème étage) The control of water flow in living organisms is central to their survival.Amphibians die in long time exposure to salt water raising many biogeographical questions abouthow oceanic islands like those...

Tba Par Aristides Arrenberg Le 27 Septembre 2017 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Tba

Internal seminar: droplet generation and vestibular sensing Par Manon Valet and Geoffrey Migault Le 20 Septembre 2017 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Manon will speak about "Quasi-static microdroplet production in a capillary trap" Manon's abstract: "We have developed a method to produce aqueous microdroplets in an oil phase, based on the periodic...

Deciphering the family of immune cells at the single cell level Par Leïla Périé (Institut Curie) Le 13 Septembre 2017 à 11h00 - Salle de réunion LJP (tour 32-33, 5ème étage) How heterogeneous systems of cells constituting multicellular organisms establish, organize and achieve coordination persists as a central question in natural sciences. Whereas stochastic gene or ...

Vulgariser la physique autrement Par Julien Bobroff (Laboratoire de Physique des Solides, Université Paris-Sud et CNRS) Le 21 Juin 2017 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Vous souvenez-vous du prix Nobel de physique de cette année sur la topologie dans les solides ? Faîtes le test autour de vous : il est passé relativement inaperçu, ...

Biomechanics in plants and fungi: fern sporangium catapult and invasive filamentous fungi growth Par Xavier Noblin (Institut de Physique de Nice, U. Nice et CNRS) Le 14 Juin 2017 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 In the first part, I will describe our study on ferns sporangia where negative pressures lower than -100 bar are used in this catapult-like elastic beam. ...

Optogenetic dissection of cell polarity and migration Par Mathieu Coppey (Institut Curie) Le 7 Juin 2017 à 11h00 - Salle de réunion LJP (tour 32-33, 5ème étage) The migration of eukaryotic cells requires a high coordination of molecular activities in space and time. When migrating, cells present a highly polarized state as revealed by the many subcellular ...

Extrinsic mechanical forces mediate retrograde axon extension in a developing neuronal circuit Par Marie Breau (Institut de Biologie Paris Seine) Le 24 Mai 2017 à 11h00 - Salle de réunion LJP (tour 32-33, 5ème étage) During neuronal circuit formation, neurons move towards their final location while growing axons towards their target. Whereas the biochemical guidance cues involved in neuronal migration and axon ...

The non-intuitive phenomenology of highly diverse microbial communities Par Mikhail Tikhonov (Harvard) Le 17 Mai 2017 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 The sequencing-driven revolution in microbial ecology unveiled the complexity of microbial communities that shape the health of our planet, and our own. Despite the ever-growing amount of data, our ...

Vascular colonization by Neisseria meningitidis Par Guillaume Duménil (institut Pasteur) Le 10 Mai 2017 à 11h00 - Salle de réunion LJP (tour 32-33, 5ème étage) Bacterial infection of human vasculature can lead to unregulated systemic activation of coagulation and innate immunity and rapidly becomes life threatening. Neisseria meningitidis is a vascular ...

Internal seminar LJP: Stochastic gene expression and hydrogel swelling Par Alexandre Deloupy et Thibault Bertrand Le 3 Mai 2017 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Alexandre Deloupy: Stochastic gene expression in Bacillus subtilis *** Thibault Bertrand: Dynamics of Swelling and Drying in Hydrogels"Swelling is a fundamental process in biology, engineering, and ...

Dendritic and cellular mechanisms of spatial representations in the brain Par Christoph Schmidt-Hieber (Institut Pasteur) Le 26 Avril 2017 à 11h00 - Salle de réunion LJP (tour 32-33, 5ème étage) How are neuronal codes of the spatial environment generated at thelevel of synapses, neurons, and neuronal circuits? Neurons in layer 2of the medial entorhinal cortex (MEC2) fire spikes at regular ...

Protein phase transitions in and out of cells Par Ned Wingreen (Physics Dept., Princeton University, USA) Le 18 Avril 2017 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Biologists have recently come to appreciate that eukaryotic cells are home to a multiplicity of non-membrane bound compartments, many of which form and dissolve as needed for the cell to function. ...

Confotronic Machines Par Igor Kulic (CNRS, Institut Charles Sadron, Strasbourg) Le 5 Avril 2017 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Many biological structures including viral capsids,  transmembrane proteins and filaments (DNA, F-actin , bacterial flagella and microtubules) are well known to undergo conformational ...

Ecological scaffolding and the origins of multicellularity Par Paul B Rainey (New Zealand Institute for Advanced Study and ESPCI) Le 29 Mars 2017 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 The evolution of multicellular life from unicellular predecessors marks a Major Evolutionary Transition that underpins the emergence of biological complexity.  Cooperation is central to the ...

AG LJP Par Jean Perrin Le 22 Mars 2017 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 -

Disordered actomyosin contracts in unexpected ways Par Martin Lenz (LPTMS of CNRS and Université Paris-Sud) Le 15 Mars 2017 à 11h00 - Disordered actomyosin contracts in unexpected ways The motion of living cells is in large part due to the interaction of semi-flexible actin filaments (F-actin) and myosin molecular motors, which induce the relative sliding of F-actin. It is often ...

Cytoskeletal Mechanics: Contractile Actomyosin Networks Par François Nédélec (Cell Biology and Biophysics, EMBL Heidelberg, Germany) Le 8 Mars 2017 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 with Julio Belmonte and Maria Leptin The cytoskeleton drives many essential processes in vivo, but for this the system of filaments will arrange itself into different overall spatial organizations, ...

Soutenance HdR de Raphaël Candelier Par Raphael Candelier (LJP/UPMC et CNRS) Le 21 Février 2017 à 10h30 - Amphithéâtre Charpak Raphaël Candelier a le plaisir de vous inviter à sa soutenance d'habilitation à diriger des recherches qui se tiendra le mardi 21 février à 10h30 à ...

Cell shape, microtubule asters and early embryonic development Par Nicolas Minc (Institut Jacques Monod, U. Paris Diderot) Le 1 Février 2017 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Life for all animals starts with the fertilization of the egg, followed by the centration of the sperm nucleus and a 3D-choreography of reductive cell divisions called cleavage patterns. These ...

Instabilities in Bacterial Biofilms Par Carine Douarche (LPS, Université Paris Sud) Le 25 Janvier 2017 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 When observing the morphogenesis of Bacillus subtilis floating biofilms, we detect some kinds of bacteria self-assemblies at the liquid-air interface that further undergo a bioconvection process. ...

Diversity of immune receptor repertoires Par Aleksandra Walczak (LPT, ENS) Le 11 Janvier 2017 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Recognition of pathogens relies on the diversity of immune receptor proteins. Recent experiments that sequence the entire immune cell repertoires provide a new opportunity for quantitative insight ...

Polarizing tissue morphogenesis by mechanical stress Par Michel Labouesse (IBPS, UPMC) Le 4 Janvier 2017 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 We are using a simple model, the nematode C. elegans, to analyze how mechanical forces influence specific cellular processes and conversely on how tissues withstand forces during morphogenesis. The C....

Journée PCC / LJP Par Physico-Chimie Curie et Laboratoire Jean Perrin Le 9 Décembre 2016 à 09h00 - TBA -

Environment sensing during bacterial collective motions Par Rémy Colin, MPI for terrestrial microbiology, Marburg, Allemagne Le 7 Décembre 2016 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Flagellated bacteria, such as Escherichia coli, swim by a succession of more or less straight runs and short reorientations, the tumbles. The bacteria probe their environment while swimming through ...

Some physical aspects of single-cell mechanosensing Par Atef Asnacios (MSC, Paris Diderot) Le 30 Novembre 2016 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 As part of their physiological functions, most cells need to adapt to their mechanical environment. In particular, the rigidity of the extracellular matrix was shown to control cell traction forces, ...

AG Par - Le 18 Novembre 2016 à 11h00 - Seminar room LJP (tour 32-33, 5th floor) -

Examining prokaryotic community behavior using 3D printing Par Aimee K. Wessel (Institut Pasteur) Le 16 Novembre 2016 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Bacterial communities engage in social activities, exhibiting behaviors such as communicating with small signaling molecules (quorum sensing [QS]) and building antibiotic-resistant biofilms. Most of ...

Mechanosensitivity of junctional beta-catenin: from mesoderm mechanotransductive evolutionary origins to tumorigenic mechanical induction Par Emmanuel Farge ( Mechanics and Genetics of Embryonic Development group, UMR168, Institut Curie, 11 rue Pierre et Marie Curie 75005 Paris, France.) Le 18 Octobre 2016 à 11h00 - Salle de réunion LJP (tour 32-33, 5ème étage) Bilaterians are complex organisms, characterized by the existence of a mesoderm tissue from which most of animal complex organs develop. Mesoderm emerged 570 millions years ago from cnidarians that ...

The many faces of emulsions Par Léa-Laetitia Pontani (INSP, UPMC) Le 11 Octobre 2016 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 We use emulsions as a model system for a wide range of applications: from the study of biomimetic tissues to the production of patchy particles for self assembly, or the exploration of granular matter...

Mean first-passage times of non-Markovian random walkers in confinement Par Raphael Voituriez (LJP /UPMC) Le 4 Octobre 2016 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 The first-passage time is a key quantity for evaluating the kinetics of various processes, and in particular chemical reactions involving "small" numbers of particles. A striking example is given by ...

Neural synchrony in early sensory processing Par Romain Brette Le 27 Septembre 2016 à 11h00 - Seminar room LJP (tour 32-33, 5th floor) What is neural synchrony good for? First, I will show that, whether synchrony has a functional role or not, neurons are extremely sensitive to coincidences among its inputs. To understand the ...

Structures and dynamics of visual and auditory cortex: cortical waves detections Par Luc Faubert (Unit of Neuroscience, Information & Complexity, CNRS-FRE 3693, Gif/Yvette) Le 20 Septembre 2016 à 11h00 - Salle de réunion LJP (tour 32-33, 5ème étage) -

AG du labo Par - Le 13 Septembre 2016 à 10h30 - Salle de séminaires 5ème étage, Tour 32-33 -

Soutenance de thèse Par Laure Claverie Le 7 Juillet 2016 à 14h00 - l'amphi Charpak, Patio 22-33. Les rongeurs utilisent leurs vibrisses pour sonder tactilement leur environnement. Tout contact induit des contraintes mécaniques lentes quasi-statiques et rapides vibratoires, qui se propagent...

Multiphoton imaging of developing tissues: multimodal, multicolor and light-sheet approaches Par Emmanuel Beaurepaire & Willy Supatto Le 28 Juin 2016 à 11h00 - Seminar room LJP (tower 32-33, 5th floor) Modern issues in systems biology require tissue-scale measurements of multiple cell parameters. Multiphoton fluorescence microscopy has proven invaluable for tissue studies with its ability to provide...

Engineering chemical organization using DNA-based reaction networks Par Adrian Zambrano Le 21 Juin 2016 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 We are inspired by the morphogenesis processes that are involved in the emergence of shape and structure in living systems. We aim to engineer chemical and material organization using the two most ...

Novel Multispectral Imaging Technique for the wide field quantification of optical properties Par Veronica Sorgato (CEA de Grenoble) Le 14 Juin 2016 à 11h00 - Novel Multispectral Imaging Technique for the wide field quantification of optical properties The Novel Multispectral Imaging Technique that has been developed, intends to aid oral cancer diagnosis by providing quantitative spatial maps of absorption and diffusion properties obtained through ...

Cortex à la demande: circuit disinhibiteur du cortex cérébelleux. Par Stéphane Dieudonné (IBENS , Paris, France) Le 7 Juin 2016 à 11h00 - Seminar room LJP, 5th floor The cerebellum plays an essential role in coordinating sensori-motor integration and motor execution. In the classical view of the cerebellum, sensory-motor inputs carried by the mossy fibers are ...