Bottom up synthetic cellularity By Dora Tang (Max Plank Institute for Cellular Molecular Biology and Genetics, Dresden) September 6, 2019 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) Living cells are well equipped in exploiting a large number of out of equilibrium processes to support life. A complete understanding of these mechanisms is still in its infancy due to the complexity ...

Réaliser le bilan carbone d'un laboratoire de recherche: retour d'expérience By Xavier Capet (L'OCEAN) July 10, 2019 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) -

Robustness in minimal models of biochemical oscillators By Clara del Junco (University of Chicago) July 2, 2019 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) Biochemical oscillations are ubiquitous in biology and allow organisms to properly time their biological functions. In this talk, I will discuss minimal Markov state models of non-equilibrium ...

Optical Trapping in zebrafish By Itia Favre Bulle (The University of Queensland, Australia) June 25, 2019 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) This talk will give you an overview of the use of Optical Tweezers in biology, and more specifically in zebrafish and its vestibular system. Otoliths, or ear-stones, play an important role in ...

Quantitative cell biology patchwork: studies of cell volume regulation, dynamics and m By Matthieu Piel (Institut Curie) June 18, 2019 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) Quantitative cell biology patchwork: studies of cell volume regulation, dynamics and mechanics of the cell cortex, deformation of the cell nucleus and cell migration ...

Mobilité de Saffman-Delbrück et particules colloidales en phase lamellaire By Jean-Baptiste Fournier (MSC, Paris-Diderot) June 11, 2019 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) Dans une première partie, je discuterai comment obtenir de façon approchée mais simple la loi de Saffman-Delbrück, c'est-à-dire la mobilité (vitesse / force ...

Internal Seminar By Wafa Ben Youssef / Iaroslava Golovkova June 4, 2019 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) TBA

Understanding Molecular Mechanisms of Biological Error Correction By Anatoly B. Kolomeisky (Rice University) May 28, 2019 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) One of the most fascinating features of biological systems is the ability to sustain an extraordinary high accuracy of all major cellular processes despite the stochastic nature of underlying chemical...

What can we learn from experimental fitness landscapes? By Claudia Bank (Gulbenkian Institute) May 23, 2019 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) Fitness landscapes, which map genotypes or phenotypes to fitness, have developed from a theoretical metaphor into a popular subject of experimental study. The quantification of the shape of fitness ...

AG By Jean Perrin May 21, 2019 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) AG

Evolutionary heritage is a predictor of signaling interaction in bacterial two-component regulatory systems By Mohamed Barakat, Philippe Ortet (CEA Cadarache) May 14, 2019 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) Two-component systems (TCSs) are virtually ubiquitous signaling pathways, which typically comprise a histidine kinase (HK) that monitors an external signal and a response regulator (RR) that ...

Organogénèse Physique de l'intestin By Nicolas Chevalier (MSC) May 7, 2019 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) L’intestin est une pompe et un réacteur biochimique. Sa longueur (7 m chez l’adulte) garantit une surface  d’absorption importante des nutriments et permet de ...

Modeling gas, fluid, and particle transport in the lung airway system: the curse of scales By Marcel Filoche (PMC/Polytechnique) April 16, 2019 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) The pulmonary airway system is a highly hierarchical tree-like 3D network in charge of transferring oxygen from the upper airways down to the alveolar region where the gas exchange occurs between ...

C. albicans: invasive lifestyle on a chip By Catherine Villard (Institut Curie) April 9, 2019 at 12:00AM - Seminar room LJP (tower 32-33, 5th floor) Fungi are ubiquitous in our environment. They are part of the so-called “rare biosphere” of the human microbiota, representing less than 0.1% of the microbiome in healthy individuals. ...

3-D Optical imaging of tissue dynamics: From label-free characterization of tissues to sensory-motor integration in the By Olivier Thouvenin April 2, 2019 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) Even though biological tissues are highly dynamic at many different scales, traditional optical microscopes can often enable to track only a portion of them. While the optical diffraction ...

Hierarchy and extremes in selections from pools of randomized proteins By Clément Nizak (ESPCI) March 26, 2019 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) Variation and selection are the core principles of Darwinian evolution, but quantitatively relating the diversity of a population to its capacity to respond to selection is challenging. Here, we ...

How the enteric pathogen Shigella invades and destroys the gut: from molecular study to mechanobiology By Nathalie Sauvonnet (Pasteur) March 19, 2019 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) Shigella is an enteroinvasive bacterium that induces human bacillary dysentery. The delivery of 30 bacterial effectors inside host cells allows the bacteria to invade colon epithelial cells, lyse the ...

Calcium dynamics in neurons, extreme statistics and role of redundancy in molecular transduction By David Holcman (ENS/IBENS) March 12, 2019 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) Calcium plays a critical role in several synaptic transduction pathways. We report and discuss here fast calcium transients and how they are possible in dendritic spines. The talk will discuss fast ...

Active sieving : from flapping nano-doors to vibrating nanotubes By Sophie Marbach (LPS/ENS) March 5, 2019 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) Filtering specific molecules is a challenge faced for several vital needs: from biomedical applications like dialysis to the intensive production of clean water. The domain has been boosted over the ...

Exclusion, congestion, and the evolution of collective action By Jorge Peña (IAST, Toulouse) February 26, 2019 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) Collective action occurs when individuals work together to provide a collective good. Examples abound in the social and natural sciences: humans collectively build houses, roads, and walls; lions work...

Understanding and steering microbial ecosystems for environmental biotechnologies: how does energy shape microbial co By Théodore Bouchez (Irstea) February 19, 2019 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) Microbes are the most abundant living entities on earth and are key engines that drive earth's biogeochemical cycles. I will first briefly illustrate some of our research activities for better ...

Impact of gut microbiota on adult brain plasticity By Gabriel Lepousez (Institut Pasteur) February 12, 2019 at 11:00AM - Seminar room LJP (tower 32-33, 5th floor) New neurons are continuously generated in only a few areas of the adult mammalian brain--the olfactory bulb and the dentate gyrus--where they integrate into already functioning circuitry. In these ...

Task engagement induces population-level behavioral representations in primary auditory cortex By Yves Boubenec (Département d'études cognitives, ENS) February 5, 2019 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Primary sensory cortices are classically considered to extract and represent stimulus features, while association and higher-order areas are thought to carry information about stimulus meaning. Here ...

Learning to soar using atmospheric thermals. By Jérôme Wong Ng (Institut Pasteur) January 29, 2019 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 In a similar way to bacteria that have to navigate in their environment, soaring birds try to minimize their effort by finding and exploiting ascending currents. However the environment is highly ...

Spying on cells with glowing chemical-genetic hybrids By Arnaud Gautier (ENS Chimie) January 22, 2019 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Deciphering the complex mechanisms controlling cells and organisms requires effective imaging systems and fluorescent probes to observe and quantify biomolecules in real time with high spatiotemporal ...

Antigenic evolution of viruses in host populations By Igor Rouzine (Sorbonne Université - LCQB) January 15, 2019 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 To escape immune recognition in previously infected hosts, viruses evolve genetically in immunologically important regions. The host’s immune system responds by generating new memory cells ...

AG By LJP December 11, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 AG

Internal Seminar By Anis Senoussi / Ananyo Maitra November 27, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 TBA

Insect navigation: lessons from walking ants and crawling larvae By Antoine Wystrach (Centre de Recherches sur la Cognition Animale, Toulouse) November 20, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 The remarkable navigational abilities of insects are proof that small brains can produce exquisitely efficient, robust navigation in complex environments. We will see here how such behaviours can ...

Understanding spatiotemporal stoichiometry of proteins in living cells / A global view on HIV-1 fusion By Sergi Padilla / Luis Alvarez (Oxford) November 14, 2018 at 02:00PM - Salle de séminaires 5ème étage, Tour 32-33 Number and Brightness : from theory to practice in understanding spatiotemporal stoichiometry of proteins in living cells - Luis Alvarez The study of protein spatiotemporal time resolved dynamics in ...

DNA microgels and microdroplets toward artificial cell-like systems By Masahiro Takinoue (Tokyo Institute of Technology) November 13, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 In recent years, the study of DNA hydrogels has been actively continued in the wide range of research fields from biophysical basic science to biological applications. However, the behaviors of DNA ...

A sneak peak with light into opaque materials By Sylvain Gigan (LKB) November 6, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Complex heterogeneous materials, that scatter light in a highly complex way, present a huge challenge for imaging (think of seeing inside or through milk or biological tissues) and a very interesting ...

Illuminating the regulation of bacterial DNA repair and mutagenesis using single-molecule and single-cell microscopy By Stephan Uphoff (Oxford) October 16, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Evolutionary processes are driven by diverse molecular mechanisms that act in the creation and prevention of mutations. It remains unclear how these mechanisms are regulated because limitations of ...

Active depinning of bacterial droplets: The collective surfing of Bacillus subtilis By Adrian Daerr (MSC, Univ Paris Diderot) October 9, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 How systems are endowed with migration capacity is a fascinating question with implications ranging from the design of novel active systems to the control of microbial populations. Bacteria, which can...

L'impact potentiel des microorganismes sur la chimie et la physique des nuages By Anne-Marie Delort (Institut de Chimie de Clermont-Ferrand) October 2, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33

Phage-bacteria interactions in the mouse gut By Marianne De Paepe (Institut Micalis, INRA) September 18, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 While it is clear that bacteriophages, the viruses that infect bacteria, abound in all bacterial communities, their role in the ecology of these communities remains poorly understood. In particular, ...

Shapes and dynamics of lipid membrane systems: from pulsatile artificial vesicles to intracellular membrane structures By Morgan Chabanon (UCSD) September 11, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Cellular lipid bilayers are found to display incredibly diverse shapes and dynamics, both at the plasma membrane and at membrane bound organelles. To understand the relationship between the complex ...

Yeast rockets, or how do growing microbial colonies generate their own propelling flow in liquids By Severine Atis (Harvard) September 7, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Transport phenomena shape and constantly reorganize materials at every scale, influencing their dispersion, segregation and clustering. Range expansions coupled with fluid flows are of great ...

Self-organization of motors, bundlers and microtubules By Thomas Surrey, The Francis Crick Institute, London September 3, 2018 at 02:00PM - Salle de séminaires 5ème étage, Tour 32-33 During cell division, the bipolar spindle self-assembles and segregates the genetic material of the cell. For this task, microtubules are arranged in space and time by motor proteins and ...

Collective behaviors of motile bacteria By Victor Sourjik (Max Planck Institute for Terrestrial Microbiology, Marburg) August 30, 2018 at 02:30PM - Salle de séminaires 5ème étage, Tour 32-33 Bacterial motility and chemotaxis are typically viewed as single-cell behaviors, used by individual bacteria to identify conditions that are favorable for growth. For the well-studied model ...

Surfing Energy Landscapes in Self-Assembling Systems: From trapped states to fueled matter with programmable lifetimes By Andreas Walther (Albert-Ludwigs-University Freiburg) June 26, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Synthetic self-assembling systems have largely been developed with a focus on equilibrium structures. Such structures have become switchable by integration of responsive elements, which is the basis ...

DNA double strand break repair in single E. coli cells By Meriem El Karoui (The University of Edimbourgh) June 19, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 It has been shown in recent years that even genetically identical cells behave differently because many central processes involve molecules present in small numbers. The inherent randomness of ...

Functions promoting the rise and fall of bacterial biofilms By Jean-Marc Ghigo (Institut Pasteur) June 12, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Surface-attached bacterial communities (biofilms) are widespread and contribute to infections and biofouling in medical and industrial settings. The dense and highly heterogeneous biofilm environment ...

Understanding the coupling between nucleosome and transcription factor dynamics By Michael Poirier June 5, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 The physical organization of all eukaryotic genomes is evolutionarily conserved. Histone protein octamers repeatedly wrap genomic DNA into nucleosomes to form long chromatin fibers. Nucleosomes and ...

To move, or not to move, that is the evolutionary question: Evolution of growth and dispersal in bacterial populations. By Maxime Deforet May 30, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 I will present two projects demonstrating the interplay between growth and dispersal in evolutionary contexts. In the first one, I focus on the evolution of expanding populations, such as bacterial ...

Le treuil élastocapillaire en une et deux dimensions By Sébastien Neukirch (Institut Jean le Rond d'Alembert) May 15, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Nous parlerons d'élasto-capillarité, domaine mellant la déformation des structures élastiques et les forces de tension de surface. En effet, les forces capillaires que ...

High-resolution mapping of bifurcations in nonlinear biochemical circuits By Anthony Genot (LIMMS/U. Tokyo, Japan) April 10, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 DNA has emerged in the past decades as a versatile and powerful polymer to build and program at the nanoscale. A rich library of devices has been built with DNA: origamis [1], biochemical neural ...

Phototaxis and texture perception By Sophia Karpenko et Jean-Baptiste Tomazo (LJP) March 27, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 In-mouth texture perception (Jean-Baptiste) Recent psychophysics based experimental investigations on both humans and rodents have revealed that the tongue-palate system of mammals possesses ...

Continuous model for water and electrolytes By Hélène Berthoumieux (LPTMC, UPMC) March 20, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Water plays an essential role as a solvent for a broad range of processes in nanometric confinement, for example conformational change of proteins or ion transport in biological channels. Modeling ...

Autocatalytic reaction fronts in disorder media By Laurent Talon March 14, 2018 at 11:00AM - Salle de séminaires 5ème étage, Tour 32-33 Autocatalytic reaction fronts between two reacting species, propagate as solitary waves. The coupling between autocatalytic reaction front and forced hydrodynamic flow may lead to stationary fronts ...