LJP at a glance

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  Lightsheet fluorescence microscopy

  With this microscopy technique, thin slices of the sample are illuminated perpendicularly to the direction of observation. It enables a high data thoughput and reduces the photodamage and stress induced on a living sample. At Jean Perrin, we combine lightsheet microscopy with calcium imaging to monitor the activity of tens of thousands of neurons in the zebrafish brain.

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  Machining microstructures

  Micromachining has become a serious alternative to soft photolithography to achieve surfaces with a controlled topography at micrometric scales. At Jean Perrin, we micro-machine micro-channel microstructures for microfluidics and surfaces decorated with pillars and spherical caps for studying mechanotransduction.

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  Optical fibers for diagnostics

  Transfering table-top multiphoton microscopy setups to clinical endoscopy is a challenge requiring multiple approaches. At Jean Perrin, we use proximal scanning of a multicore image-guide compatible with standard endoscopes and the distal scanning of a single microstructured fiber.

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  Millifluidics for biology

  Millifluidic devices of molded PDMS allows to impose different channel geometries and thus to fine-tune the system hydrodynamical properties. The preparation is simple, fast and reproducible. At Jean Perrin, we use this technique to study the impact of physical parameters on the development of bacterial biofilms.

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News

31
MAR 2021

Thesis defense - Benjamin Gallois
I am pleased to invite you to my thesis defense which will take place on Wednesday, March 31 at 2:00 pm and ...

05
NOV 2020

Séminaire/débat 'Monde fini': Allons-nous continuer la recherche scientifique ?'
Le prochain séminaire/débat ‘Recherche dans un monde fini’ aura lieu jeudi 5/11 ...

17
SEP 2020

Présentation de l'empreinte carbone du LJP
L'empreinte carbone du laboratoire Jean Perrin a été présentée en ...

11
SEP 2020

PhD defense - Anis Senoussi
I am pleased to invite you to the defense of my thesis which will take place on Friday, September 11th at...

29
JUN 2020

A basic physical mechanism enables cell migration in absence of adhesion
Many cell types within the organism bind to their environment via specific adhesion molecules (integrins); ...

23
JUN 2020

PhD defense - Loïc Marrec
I am pleased to announce that I will defend my thesis this Tuesday, June 23rd at 2:30 pm.It will take place by...

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