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Clément Nizak
Directeur de recherche CNRS ORCID 0000-0002-4591-8240
Bureau (pièce 518)
01 44 27 28 23

Thématiques de recherche

EvoMorph - Evolution & Morphogenèse dans les systèmes moléculaires

Présentation

My current research focuses on enzymes and antibodies as experimental models to tackle fundamental questions related to bio-molecule function and evolution. Our large-scale experiments are based on droplet microfluidics, phage display and high-throughput DNA sequencing technologies, and downstream statistical analysis. Our approaches are strongly motivated by computational analysis of genomic data and theory inspired by statistical physics.

I work in close collaboration with Olivier Rivoire (Statistical Biology, CIRB-College de France).

I teach the Biostatistics of the IBP Ms program at Sorbonne Université and part of the Biophysics course at ESPCI Paris.

 

ResearcherID and Google Scholar

Peer-reviewed articles:

2021

2020

  • A. Gerard, A. Woolfe, G. Mottet, M. Reichen, C. Castrillon, V. Menrath, S. Ellouze, A. Poitou, R. Doineau, L. Briseño-Roa, P. Canales-Herrerias, P. Mary, G. Rose, C. Ortega, M. Delince, S. Essono, B. Jia, B. Iannascoli, O. Richard-LeGoff, R. Kumar, Y. Pousse, B. Shen, K. Grosselin, B. Saudemont, A. Sautel-Caillé, A. Godina, S. McNamara, K. Eyer, G. Millot, J. Baudry, P. England, C. Nizak, A. Jensen, A. Griffiths, and C. Brenan, "High-throughput single-cell activity-based screening and sequencing of antibodies using droplet microfluidics." Nature Biotechnology, vol. 38, no. 6, pp. 715-721, 2020.

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