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MAY
Three-dimensional “cellular ballons” or cysts: microfluidic formation, growth, deformability, instabilities.
By Pierre Nassoy - Laboratoire de Photonique Numérique et Nanosciences (LP2N) - Univ. Bordeaux - Talence
May 28, 2024 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 32-33 - 5th Floor - P533

Abstract

Organoids are lumen-containing multicellular structures that recapitulate key features of the organs. We will first present a microfluidic technology that allows to produce them at high throughput in individual hydrogel capsules. Then we will investigate their growth dynamics, their unique mechanical properties and some instabilities that are remarkably reminiscent of stages in embryo development