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Sergei Kruglik
Research Engineer at SU
Office (room 406)
(+33) 1 44 27 23 36

Research interests

Biomembrane plasticity and cellular function

Presentation


Publications

2024

Identification of extracellular vesicles from their Raman spectra via self-supervised learning - Scientific Reports (Mar. 2024)
M.N. Jensen , E.M. Guerreiro , A. Enciso-Martinez , S.G. Kruglik , C. Otto , O. Snir , B. Ricaud , O.G. Hellesø
  URL Full text PDF Bibtex doi:10.1038/s41598-024-56788-7
Lipidomics and biodistribution of extracellular vesicles-secreted by hepatocytes from Zucker lean and fatty rats - Journal of Extracellular Biology (Feb. 2024)
M. Azparren-Angulo , J. Mleczko , O.E. Alboniga , S.G. Kruglik , J.M. Guigner , E. Gonzalez , C. Garcia-Vallicrosa , J. Llop , C. Simó , C. Alonso , M. Iruarrizaga , F. Royo , J.M. Falcon-Perez
  URL Full text PDF Bibtex doi:10.1002/jex2.140
Extracellular vesicles from activated platelets possess a phospholipid-rich biomolecular profile and enhance prothrombinase activity - Journal of Thrombosis and Haemostasis (Jan. 2024)
E.M. Guerreiro , S.G. Kruglik , S. Swamy , N. Latysheva , B. Østerud , J.M. Guigner , F. Sureau , S. Bonneau , A.N. Kuzmin , P.N. Prasad , J.B. Hansen , O.G. Hellesø , O. Snir
  URL Full text PDF Bibtex doi:10.1016/j.jtha.2024.01.004

2023

Dynamics of mitochondrial under oxidative stress with high spatiotemporal resolution - Front. Cell Dev. Biol. (Nov. 2023)
V. Loriette, , A. Fragola, , S. Kruglik , S. Sridhar, , A. Hubert , F. Orieux, , E. Sepulveda, , F. Sureau , S. Bonneau
  URL Full text PDF Bibtex doi:https://doi.org/10.3389/fcell.2023.1307502
The H-NOX protein structure adapts to different mechanisms in sensors interacting with nitric oxide - Chemical Science (Jul. 2023)
B.K. Yoo , S.G. Kruglik , J.C. Lambry , I. Lamarre , C.S. Raman , P. Niochede , M. Negrerie
  URL Full text PDF Bibtex doi:10.1039/d3sc01685d

2021

Using single-vesicle technologies to unravel the heterogeneity of extracellular vesicles - Nature Protocols (Jul. 2021)
G. Bordanaba-Florit , F. Royo , S.G. Kruglik , J.M. Falcón-Pérez
  URL Full text PDF Bibtex doi:10.1038/s41596-021-00551-z
Multiconformational analysis of tripeptides upon consideration of implicit and explicit hydration effects - Journal of Molecular Graphics and Modelling (Jan. 2021)
B. Hernández , F. Pflüger , S.G. Kruglik , M. Ghomi
  URL Full text PDF Bibtex doi:10.1016/j.jmgm.2020.107790

2020

Structural Analysis of Nonapeptides Derived from Elastin - Biophysical Journal (Jun. 2020)
B. Hernández , J.M. Crowet , J. Thiery , S.G. Kruglik , N. Belloy , S. Baud , M. Dauchez , L. Debelle
  URL Full text PDF Bibtex doi:10.1016/j.bpj.2020.04.019

2019

Characterization of a multicore fiber image guide for nonlinear endoscopic imaging using two-photon fluorescence and second-harmonic generation - Journal of Biomedical Optics (Oct. 2019)
A. Garofalakis , S.G. Kruglik , T. Mansuryan , A. Gillibert , L. Thiberville , F. Louradour , C. Vever-Bizet , G. Bourg-Heckly
  URL Full text PDF Bibtex doi:10.1117/1.JBO.24.10.106004
Disorder-to-Order Markers of a Cyclic Hexapeptide Inspired from the Binding Site of Fertilin Beta Involved in Fertilization Process - ACS Omega (Oct. 2019)
B. Hernández , P. Legrand , S. Dufay , R. Gahoual , S. Sanchez-Cortes , S.G. Kruglik , J. Fabreguettes , J. Wolf , P. Houzé , M. Ghomi
  URL Full text PDF Bibtex doi:10.1021/acsomega.9b01885
Raman Tweezers Microspectroscopy of Functionalized 4.2-nm Diameter CdSe Nanocrystals in Water Reveals Changed Ligand Vibrational Modes by a Metal Cation - Journal of Physical Chemistry C (Sep. 2019)
R. Mrad , S.G. Kruglik , N. Ben Brahim , R. Ben Chaabane , M. Negrerie
  URL Full text PDF Bibtex doi:10.1021/acs.jpcc.9b06756
Lipid unsaturation properties govern the sensitivity of membranes to photo-induced oxidative stress - Biophysical Journal (Mar. 2019)
A. Bour , S.G. Kruglik , M. Chabanon , P. Rangamani , N. Puff , S. Bonneau
  URL Full text PDF Bibtex doi:10.1016/j.bpj.2019.01.033
Raman tweezers microspectroscopy of circa 100 nm extracellular vesicles - Nanoscale (Jan. 2019)
S.G. Kruglik , F. Royo , J.M. Guigner , L. Palomo , O. Seksek , P.Y. Turpin , I. Tatischeff , J.M. Falcon-Pérez
  URL Full text PDF Bibtex doi:10.1039/c8nr04677h

2018

Assessment of the ability of poly(l-lysine)-poly(ethylene glycol) (PLL-PEG) hydrogels to support the growth of U87-MG and F98 glioma tumor cells - J. Appl. Polym. Sci. (Jun. 2018)
E. Gontran , M. Juchaux , C. Deroulers , S. Kruglik , N. Huang , M. Badoual , O. Seksek
  URL Full text PDF Bibtex doi:10.1002/app.46287
Phosphorescence Kinetics of Singlet Oxygen Produced by Photosensitization in Spherical Nanoparticles. Part I. Theory - J. Phys. Chem. B (May. 2018)
A. Hovan , S. Datta , S.G. Kruglik , D. Jancura , P. Miskovsky , G. Bano
  URL Full text PDF Bibtex doi:10.1021/acs.jpcb.8b00658
Phosphorescence Kinetics of Singlet Oxygen Produced by Photosensitization in Spherical Nanoparticles. Part II. The Case of Hypericin-Loaded Low-Density Lipoprotein Particles - J. Phys. Chem. B (May. 2018)
S. Datta , A. Hovan , A. Jutkova , S.G. Kruglik , D. Jancura , P. Miskovsky , G. Bano
  URL Full text PDF Bibtex doi:10.1021/acs.jpcb.8b00659
Dynamical Behavior of Somatostatin-14 and Its Cyclic Analogues as Analyzed in Bulk and on Plasmonic Silver Nanoparticles - Advances in Protein Chemistry and Structural Biology (Feb. 2018)
B. Hernandez , Y.M. Coïc , E.L. Tobar , S. Sanchez-Cortez , B. Baron , F. Pfluger , S.G. Kruglik , R. Cohen , M. Ghomi
  URL Full text PDF Bibtex doi:10.1016/bs.apcsb.2018.01.002

2017

Structural changes and picosecond to second dynamics of cytochrome c in interaction with nitric oxide in ferrous and ferric redox states - Physical Chemistry Chemical Physics (Aug. 2017)
S.G. Kruglik , B.K. Yoo , J.C. Lambry , J.L. Martin , M. Negrerie
  URL Full text PDF Bibtex doi:10.1039/c7cp02634j
Photo-induced oxidation of bio-mimetic membranes : Giant pore openings and membrane defects - Eur. Biophys. J. Biophys. Lett. (Jul. 2017)
A. Bour , S. Kruglik , N. Puff , S. Bonneau
  URL Full text PDF Bibtex doi:
Raman scattering-based multiconformational analysis for probing the structural differences between acetylcholine and acetylthiocholine. - Journal of Pharmaceutical and Biomedical Analysis (Mar. 2017)
B. Hernández , P. Houzé , F. Pflüger , S.G. Kruglik , M. Ghomi
  URL Full text PDF Bibtex doi:10.1016/j.jpba.2017.01.049

2016

From bulk to plasmonic nanoparticle surfaces: the behavior of two potent therapeutic peptides, octreotide and pasireotide - Physical Chemistry Chemical Physics (Sep. 2016)
B. Hernandez , E. Lopez-Tobar , S. Sanchez-Cortes , Y.M. Coic , B. Baron , A. Chenal , S.G. Kruglik , F. Pfluger , R. Cohen , M. Ghomi
  URL Full text PDF Bibtex doi:10.1039/c6cp04421b
All characteristic Raman markers of tyrosine and tyrosinate originate from phenol ring fundamental vibrations - Journal of Raman Spectroscopy (Feb. 2016)
B. Hernandez , Y.M. Coic , F. Pflueger , S.G. Kruglik , M. Ghomi
  URL Full text PDF Bibtex doi:10.1002/jrs.4776

2015

Protonation-deprotonation and structural dynamics of antidiabetic drug metformin - Journal of Pharmaceutical and Biomedical Analysis (Oct. 2015)
B. Hernandez , F. Pflueger , S.G. Kruglik , R. Cohen , M. Ghomi
  URL Full text PDF Bibtex doi:10.1016/j.jpba.2015.04.041
Whole-brain functional imaging with two-photon light-sheet microscopy - Nature Methods (Apr. 2015)
S. Wolf , W. Supatto , G. Debregeas , P. Mahou , S.G. Kruglik , J.M. Sintes , E. Beaurepaire , R. Candelier
  URL Full text PDF Bibtex doi:10.1038/nmeth.3371

2014

Low Concentration Structural Dynamics of Lanreotide and Somatostatin-14 - Biopolymers (Oct. 2014)
B. Hernandez , Y.M. Coic , B. Baron , S.G. Kruglik , F. Pflueger , R. Cohen , C. Carelli , M. Ghomi
  URL Full text PDF Bibtex doi:10.1002/bip.22491
Disulfide linkage Raman markers: a reconsideration attempt - Journal of Raman Spectroscopy (Aug. 2014)
B. Hernandez , F. Pflueger , E. Lopez-Tobar , S.G. Kruglik , J.V. Garcia-Ramos , S. Sanchez-Cortes , M. Ghomi
  URL Full text PDF Bibtex doi:10.1002/jrs.4521
Raman characterization of Avocado Sunblotch viroid and its response to external perturbations and self-cleavage - BMC Biophysics (Mar. 2014)
G. Hui-Bon-Hoa , H. Kaddour , J. Vergne , S.G. Kruglik , M.C. Maurel
  URL Full text PDF Bibtex doi:10.1186/2046-1682-7-2

2013

Protonation-deprotonation of the glycine backbone as followed by Raman scattering and multiconformational analysis - Chemical Physics (Nov. 2013)
B. Hernandez , F. Pflueger , S.G. Kruglik , M. Ghomi
  URL Full text PDF Bibtex doi:10.1016/j.chemphys.2013.08.008
Characteristic Raman lines of phenylalanine analyzed by a multiconformational approach - Journal of Raman Spectroscopy (Jun. 2013)
B. Hernandez , F. Pflueger , S.G. Kruglik , M. Ghomi
  URL Full text PDF Bibtex doi:10.1002/jrs.4290
Label free multiphoton imaging of human pulmonary tissues through two-meter-long microstructured fiber and multicore image-guide - ENDOSCOPIC MICROSCOPY VIII (Jan. 2013)
G. Ducourthial , C. Lefort , D.A. Peyrot , T. Mansuryan , S.G. Kruglik , C. Vever-Bizet , L. Thiberville , F. Lacombe , G. Bourg-Heckly , F. Louradour
  URL Full text PDF Bibtex doi:10.1117/12.2003118

2012

Fast characterisation of cell-derived extracellular vesicles by nanoparticles tracking analysis, cryo-electron microscopy, and Raman tweezers microspectroscopy - Journal of Extracellular Vesicles (Nov. 2012)
I. Tatischeff , E. Larquet , J.M. Falcon-Pérez , P.Y. Turpin , S.G. Kruglik
  URL Full text PDF Bibtex doi:10.3402/jev.v1i0.19179
Octreotide Used for Probing the Type-II` beta-Turn CD and Raman Markers - Journal of Physical Chemistry B (Aug. 2012)
B. Hernandez , Y.M. Coic , S.G. Kruglik , C. Carelli , R. Cohen , M. Ghomi
  URL Full text PDF Bibtex doi:10.1021/jp3036428
Development of a nonlinear fiber-optic spectrometer for human lung tissue exploration - Biomedical Optics Express (May. 2012)
D.A. Peyrot , C. Lefort , M. Steffenhagen , T. Mansuryan , G. Ducourthial , D. Abi-Haidar , N. Sandeau , C. Vever-Bizet , S.G. Kruglik , L. Thiberville , F. Louradour , G. Bourg-Heckly
Absorption Band III Kinetics Probe the Picosecond Heme Iron Motion Triggered by Nitric Oxide Binding to Hemoglobin and Myoglobin - Journal of Physical Chemistry B (Apr. 2012)
B.K. Yoo , S.G. Kruglik , I. Lamarre , J.L. Martin , M. Negrerie
  URL Full text PDF Bibtex doi:10.1021/jp300849y
Development of a non-linear endomicroscope for the in vivo in situ observation of lung tissue extracellular matrix - IRBM (Apr. 2012)
D.A. Peyrot , C. Lefort , T. Mansuryan , S.G. Kruglik , N. Sandeau , C. Vever-Bizet , L. Thiberville , F. Lacombe , F. Louradour , G. Bourg-Heckly
  URL Full text PDF Bibtex doi:10.1016/j.irbm.2012.01.011

2011

Side chain flexibility and protonation states of sulfur atom containing amino acids - Physical Chemistry Chemical Physics (Oct. 2011)
B. Hernandez , F. Pflueger , A. Adenier , S.G. Kruglik , M. Ghomi
  URL Full text PDF Bibtex doi:10.1039/c1cp21054h
Energy maps, side chain conformational flexibility, and vibrational features of polar amino acids L-serine and L-threonine in aqueous environment - Journal of Chemical Physics (Aug. 2011)
B. Hernandez , F. Pflueger , A. Adenier , M. Nsangou , S.G. Kruglik , M. Ghomi
  URL Full text PDF Bibtex doi:10.1063/1.3617415
Sub-picosecond Raman spectrometer for time-resolved studies of structural dynamics in heme proteins - Journal of Raman Spectroscopy (Mar. 2011)
S.G. Kruglik , J.C. Lambry , J.L. Martin , M.H. Vos , M. Negrerie
  URL Full text PDF Bibtex doi:10.1002/jrs.2685
Toward nonlinear endomicroscopy for exploration of the pulmonary airways: preliminary spectroscopic study of human lung tissue using a single-mode fibre - ENDOSCOPIC MICROSCOPY VI (Jan. 2011)
D.A. Peyrot , C. Lefort , D.A. Haidar , T. Mansuryan , S. Kruglik , N. Sandeau , F. Louradour , G. Bourg-Heckly
  URL Full text PDF Bibtex doi:10.1117/12.875440

2010

Vibrational Analysis of Amino Acids and Short Peptides in Hydrated Media. VIII. Amino Acids with Aromatic Side Chains: L-Phenylalanine, L-Tyrosine, and L-Tryptophan - Journal of Physical Chemistry B (Nov. 2010)
B. Hernandez , F. Pflueger , A. Adenier , S.G. Kruglik , M. Ghomi
  URL Full text PDF Bibtex doi:10.1021/jp106786j
Picosecond primary structural transition of the heme is retarded after nitric oxide binding to heme proteins - Proc. Natl. Acad. Sci. U. S. A. (Aug. 2010)
S.G. Kruglik , B.K. Yoo , S. Franzen , M.H. Vos , J.L. Martin , M. Negrerie
  URL Full text PDF Bibtex doi:10.1073/pnas.0912938107

2009

Nanovesicles released by Dictyostelium cells: A potential carrier for drug delivery - International Journal of Pharmaceutics (Oct. 2009)
F. Lavialle , S. Deshayes , F. Gonnet , E. Larquet , S.G. Kruglik , N. Boisset , R. Daniel , A. Alfsen , I. Tatischeff
  URL Full text PDF Bibtex doi:10.1016/j.ijpharm.2009.06.039
Electronic acceleration of atomic motions and disordering in bismuth - Nature (Mar. 2009)
G. Sciaini , M. Harb , S.G. Kruglik , T. Payer , C.T. Hebeisen , F.J.M.Z. Heringdorf , M. Yamaguchi , M.H.v. Hoegen , R. Ernstorfer , R.J.D. Miller
  URL Full text PDF Bibtex doi:10.1038/nature07788
Excitation of longitudinal and transverse coherent acoustic phonons in nanometer free-standing films of (001) Si - Physical Review B (Mar. 2009)
M. Harb , W. Peng , G. Sciaini , C.T. Hebeisen , R. Ernstorfer , M.A. Eriksson , M.G. Lagally , S.G. Kruglik , R. Miller
  URL Full text PDF Bibtex doi:10.1103/PhysRevB.79.094301

2008

Direct visualization of charge distributions during femtosecond laser ablation of a Si(100) surface - Physical Review B (Aug. 2008)
C.T. Hebeisen , G. Sciaini , M. Harb , R. Ernstorfer , S.G. Kruglik , R.J.D. Miller
  URL Full text PDF Bibtex doi:10.1103/PhysRevB.78.081403
Electronically driven structure changes of si captured by femtosecond electron diffraction - Physical Review Letters (Apr. 2008)
M. Harb , R. Ernstorfer , C.T. Hebeisen , G. Sciaini , W. Peng , T. Dartigalongue , M.A. Eriksson , M.G. Lagally , S.G. Kruglik , R.J.D. Miller
  URL Full text PDF Bibtex doi:10.1103/PhysRevLett.100.155504
Grating enhanced ponderomotive scattering for visualization and full characterization of femtosecond electron pulses - Optics Express (Mar. 2008)
C.T. Hebeisen , G. Sciaini , M. Harb , R. Ernstorfer , T. Dartigalongue , S.G. Kruglik , R.J.D. Miller
  URL Full text PDF Bibtex doi:10.1364/OE.16.003334

2007

Subpicosecond oxygen trapping in the heme pocket of the oxygen sensor FixL observed by time-resolved resonance Raman spectroscopy - Proc. Natl. Acad. Sci. U. S. A. (May. 2007)
S.G. Kruglik , A. Jasaitis , K. Hola , T. Yamashita , U. Liebl , J.L. Martin , M.H. Vos
  URL Full text PDF Bibtex doi:10.1073/pnas.0700445104
Molecular basis for nitric oxide dynamics and affinity with Alcaligenes xylosoxidans cytochrome c ` - Journal of Biological Chemistry (Feb. 2007)
S.G. Kruglik , J.C. Lambry , S. Cianetti , J.L. Martin , R.R. Eady , C.R. Andrew , M. Negrerie
  URL Full text PDF Bibtex doi:10.1074/jbc.M604327200

2006

Ultrafast heme dynamics in ferrous versus ferric cytochrome c studied by time-resolved resonance Raman and transient absorption spectroscopy - Journal of Physical Chemistry B (Jun. 2006)
M. Negrerie , S. Cianetti , M. Vos , J. Martin , S.G. Kruglik
  URL Full text PDF Bibtex doi:10.1021/jp0559377
Role of heme iron coordination and protein structure in the dynamics and geminate rebinding of nitric oxide to the H93G myoglobin mutant - Implications for nitric oxide sensors - Journal of Biological Chemistry (Apr. 2006)
M. Negrerie , S.G. Kruglik , J. Lambry , M. Vos , J. Martin , S. Franzen
  URL Full text PDF Bibtex doi:10.1074/jbc.M513375200

2004

Photodissociation of heme distal methionine in ferrous cytochrome c revealed by subpicosecond time-resolved resonance Raman spectroscopy - Journal of the American Chemical Society (Nov. 2004)
S. Cianetti , M. Negrerie , M. Vos , J. Martin , S.G. Kruglik
  URL Full text PDF Bibtex doi:10.1021/ja046422i

2002

Resonance CARS study of the structure of "green" and "red" chromophores within the red fluorescent protein DsRed - Journal of the American Chemical Society (Sep. 2002)
S.G. Kruglik , V. Subramaniam , J. Greve , C. Otto
  URL Full text PDF Bibtex doi:10.1021/ja0260824