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Séminaire interne
Par Darka Labavic / Julie Lafaye
Le 16 Mars 2021 à 16h00 - Salle de séminaires 5ème étage, Tour 32-33
TBA
Mesodermal growth and morphogenesis in chicken embryos
Par Karine Guevorkian (Institut Curie)
Le 9 Mars 2021 à 16h00 - Salle de séminaires 5ème étage, Tour 32-33
The life of an embryo starts as a ball of undifferentiated cells. Gradually, biochemical signals, in concert with mechanical cues, pattern the embryonic tissues from which organs emerge. Understanding...
Modelling Immune Recognition with Restricted Boltzmann Machines
Par Barbara Bravi (LPENS)
Le 15 Décembre 2020 à 16h00 - Zoom
The immune response of an organism when it is infected by a pathogen is based on the recognition of small portions of its proteins. This raises two questions: what protein portions are relevant to ...
Chirality and non-reciprocal interactions: Creating new liquid crystals from activity
Par Ananyo Maitra (Laboratoire Jean Perrin)
Le 8 Décembre 2020 à 15h00 - Zoom
Active matter theories generally augment descriptions of passive liquid crystals with nonequilibrium forces and currents, thereby addressing how activity affects these structures. In this talk, I will...
Understanding the mechanics of coordinated tissue movements in zebrafish gastrulation
Par Silvia Grigolon (Laboratoire Jean Perrin)
Le 1 Décembre 2020 à 16h00 - Zoom
Embryo morphogenesis relies on highly coordinated movements of different tissues as well as cell differentiation and patterning. However, remarkably little is known about how tissues coordinate their ...
Spatio-temporal patterning of living cells with extracellular DNA programs
Par Marc Van Der Hofstadt (Laboratoire Jean Perrin)
Le 24 Novembre 2020 à 11h00 - Zoom
The microenvironment surrounding eukaryotic cells in complex organisms is constantly evolving. Its out-of-equilibrium behaviour is due to the perpetual production and degradation of its constituents ...
Eukaryotic cells as interacting living particles
Par Joseph d’Alessandro (Institut Jacques Monod, Paris)
Le 17 Novembre 2020 à 11h00 - Zoom
Cells move. They propel themselves using an internal machinery which endows them with the characteristics of active particles. At the same time, they interact dynamically with their environment and ...
Fluid pumping, lumen nucleation and electro-hydraulic phenomena in cell assemblies
Par Charlie Duclut (Max Planck, Dresden)
Le 10 Novembre 2020 à 11h00 - Zoom
In addition to generating forces and reacting to mechanical cues, cell assemblies and tissues are characterized by their capacity to actively pump fluid, thanks to active ion transport. By pumping ...
Single-molecule analysis of multicomponent DNA repair pathways
Par Terence Strick (ENS)
Le 10 Mars 2020 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
DNA repair is typically a multi-step, multi-component process in which proteins detect a DNA lesion; confirm the presence of the lesion; excise the lesion; and replace the excised DNA with ...
Seminaire Interne
Par Hugo Trentesaux / Aurore Woller
Le 3 Mars 2020 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
TBA
Linking lineage and population observables in growing cell populations
Par David Lacoste (ESPCI)
Le 25 Février 2020 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
The question of how a cell controls its size is an one, which despite decades of research is still timely because the old experiments have been unable to measure the heterogeneity of cell populations ...
Microfabricated tools to study embryonic patterning in vitro
Par Benoît Sorre (MSC)
Le 4 Février 2020 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
One of the most striking features of embryonic development is that differentiation is happening in a spatially ordered fashion: tissue self-organize to form well-defined patterns that pre-figure the ...
Natural selection of compartmentalized autocatalytic chemical reactions
Par Philippe Nghe (ESPCI)
Le 21 Janvier 2020 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
Natural selection, the differential reproduction and survival (differential fitness) of individuals due to differences in phenotype, is an essential component of evolution in biological systems. ...
Emerging order, from crystals of colloids to fish schools
Par Sophie Ramananarivo (LadHyX Polytechnique)
Le 7 Janvier 2020 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
Living systems constantly exploit active fluctuations in their processes, to boost transport or assist assembly. Self-propelled colloids, that consume energy to move hold the same potential for ...
Modelling and predicting antigen presentation with Restricted Boltzmann Machines
Par Barbara Bravi (ENS)
Le 17 Décembre 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
Immune recognition of infected and malignant cells requires presentation on their surface of antigens (i.e. short peptides) by human leukocyte antigen class I (HLA-I) proteins, which are coded by one ...
Soft Matter for the Origin of Life: Liquid Crystals, Phase Transitions and the Prebiotic Emergence of Biopolymers
Par Tommaso P. Fraccia (IPGG - ESPCI)
Le 12 Décembre 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
The abiotic formation of biopolymers from their monomeric building blocks and the emergence of cellular structures are still unsolved problems in the origin of life investigation. In this frame soft ...
Retinal computations and circuits integrating contextual information
Par Olivier Marre (Institut de la vision)
Le 10 Décembre 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
At the retinal output, a common assumption is that ganglion cells of a single type extract a single stimulus feature from the visual scene to form a feature map. Yet they can also respond to very ...
Can a population targeted by an artificial gene drive be rescued?
Par Florence Débarre (Sorbonne Université)
Le 3 Décembre 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
Gene drive, a type of genetic control, consists in using selfish genetic elements to modify or eradicate populations. The idea is not new, but has only recently become feasible, thanks to the ...
Cytoskeletal crosstalk during cell migration
Par Sandrine Etienne-Manneville (Pasteur)
Le 26 Novembre 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
Cell migration requires a dramatic and coordinated reorganization of the different elements of the cytoplasmic cytoskeleton, composed of three types of filamentous structures: actin microfilaments, ...
Deep learning driven model discovery in biology and physics
Par Remy Kusters (CRI)
Le 19 Novembre 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
As scientific data sets become richer and increasingly complex, machine learning (ML) tools become more useful and widely applied. Discovering a mechanistic model, rather than predicting the outcome ...
Formation and functionalization of cellular lipid droplets
Par Abdou Rachid Thiam (ENS)
Le 12 Novembre 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
A key feature of cell survival is the ability to synchronously respond to environmental energy fluctuations. Excess energy is stored by cells in neutral lipid oil forms such as triglycerides and ...
Nonlinear dynamics of chemically active microdrops grants an insight into interfacial chemistry
Par Matvey Morozov (Université Libre de Bruxelles)
Le 4 Novembre 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
A chemically active microdrop that is suspended in the bulk of a reagent solution is an example of a non-equilibrium physicochemical system akin to cells and vesicles. Owing to their non-equilibrium ...
Superinfection and cure of infected cells as mechanisms for hepatitis C virus adaptation and persistence
Par Ruian Ke (Los Alamos)
Le 18 Octobre 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
RNA viruses exist as a genetically diverse quasispecies with extraordinary ability to adapt to abrupt changes in the host environment. However, the molecular mechanisms that contribute to their rapid ...
Perception de la texture en bouche : une approche biomimétique
Par Jean-Baptiste Thomazo
Le 8 Octobre 2019 à 14h00 - Amphithéâtre Durand
Le système langue-palais est capable de détecter de fines variations de texture en bouche là où le meilleur des rhéomètres est essentiellement aveugle. Une ...
The mechanobiology of vascular colonization by Neisseria meningitidis
Par Daria Bonazzi (Pasteur)
Le 8 Octobre 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
During human meningococcal infections, bacteria adhere to the endothelium, accumulate in the form of aggregates and finally fill up blood vessels, causing severe diseases such as septicemia and ...
Spontaneous shape transitions of active matter
Par Anne Bernheim-Groswasser (Ben Gurion University)
Le 4 Octobre 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
Shape transitions in developing organisms can be driven by active stresses, notably, active contractility generated by myosin motors. The mechanisms generating tissue folding are typically studied in ...
Sinister Self-Assembly - Colloidal Architecture Using DNA Origami
Par Matan Ben Zion (ESPCI)
Le 1 Octobre 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
Self-assembly and self-organization are two big challenges in natural sciences. What are the rules governing the emergence of greater structures from unassuming individuals? Does statistical ...
Séminaire interne
Par Shunichi Kashida/Guillaume Le Goc
Le 24 Septembre 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
TBA
Bottom up synthetic cellularity
Par Dora Tang (Max Plank Institute for Cellular Molecular Biology and Genetics, Dresden)
Le 6 Septembre 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
Living cells are well equipped in exploiting a large number of out of equilibrium processes to support life. A complete understanding of these mechanisms is still in its infancy due to the complexity ...
Réaliser le bilan carbone d'un laboratoire de recherche: retour d'expérience
Par Xavier Capet (L'OCEAN)
Le 10 Juillet 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
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Robustness in minimal models of biochemical oscillators
Par Clara del Junco (University of Chicago)
Le 2 Juillet 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
Biochemical oscillations are ubiquitous in biology and allow organisms to properly time their biological functions. In this talk, I will discuss minimal Markov state models of non-equilibrium ...
Optical Trapping in zebrafish
Par Itia Favre Bulle (The University of Queensland, Australia)
Le 25 Juin 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
This talk will give you an overview of the use of Optical Tweezers in biology, and more specifically in zebrafish and its vestibular system. Otoliths, or ear-stones, play an important role in ...
Quantitative cell biology patchwork: studies of cell volume regulation, dynamics and mechanics of the cell cortex, deformation of the cell nucleus and cell migration
Par Matthieu Piel (Institut Curie)
Le 18 Juin 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
Quantitative cell biology patchwork: studies of cell volume regulation, dynamics and mechanics of the cell cortex, deformation of the cell nucleus and cell migration ...
Mobilité de Saffman-Delbrück et particules colloidales en phase lamellaire
Par Jean-Baptiste Fournier (MSC, Paris-Diderot)
Le 11 Juin 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
Dans une première partie, je discuterai comment obtenir de façon approchée mais simple la loi de Saffman-Delbrück, c'est-à-dire la mobilité (vitesse / force ...
Séminaire interne
Par Wafa Ben Youssef / Iaroslava Golovkova
Le 4 Juin 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
TBA
Understanding Molecular Mechanisms of Biological Error Correction
Par Anatoly B. Kolomeisky (Rice University)
Le 28 Mai 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
One of the most fascinating features of biological systems is the ability to sustain an extraordinary high accuracy of all major cellular processes despite the stochastic nature of underlying chemical...
What can we learn from experimental fitness landscapes?
Par Claudia Bank (Gulbenkian Institute)
Le 23 Mai 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
Fitness landscapes, which map genotypes or phenotypes to fitness, have developed from a theoretical metaphor into a popular subject of experimental study. The quantification of the shape of fitness ...
AG
Par Jean Perrin
Le 21 Mai 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
AG
Evolutionary heritage is a predictor of signaling interaction in bacterial two-component regulatory systems
Par Mohamed Barakat, Philippe Ortet (CEA Cadarache)
Le 14 Mai 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
Two-component systems (TCSs) are virtually ubiquitous signaling pathways, which typically comprise a histidine kinase (HK) that monitors an external signal and a response regulator (RR) that ...
Organogénèse Physique de l'intestin
Par Nicolas Chevalier (MSC)
Le 7 Mai 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
L’intestin est une pompe et un réacteur biochimique. Sa longueur (7 m chez l’adulte) garantit une surface  d’absorption importante des nutriments et permet de ...
Modeling gas, fluid, and particle transport in the lung airway system: the curse of scales
Par Marcel Filoche (PMC/Polytechnique)
Le 16 Avril 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
The pulmonary airway system is a highly hierarchical tree-like 3D network in charge of transferring oxygen from the upper airways down to the alveolar region where the gas exchange occurs between ...
C. albicans: invasive lifestyle on a chip
Par Catherine Villard (Institut Curie)
Le 9 Avril 2019 à 12h00 - Salle de séminaires 5ème étage, Tour 32-33
Fungi are ubiquitous in our environment. They are part of the so-called “rare biosphere” of the human microbiota, representing less than 0.1% of the microbiome in healthy individuals. ...
3-D Optical imaging of tissue dynamics: From label-free characterization of tissues to sensory-motor integration in the spinal cord
Par Olivier Thouvenin
Le 2 Avril 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
Even though biological tissues are highly dynamic at many different scales, traditional optical microscopes can often enable to track only a portion of them. While the optical diffraction ...
Hierarchy and extremes in selections from pools of randomized proteins
Par Clément Nizak (ESPCI)
Le 26 Mars 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
Variation and selection are the core principles of Darwinian evolution, but quantitatively relating the diversity of a population to its capacity to respond to selection is challenging. Here, we ...
How the enteric pathogen Shigella invades and destroys the gut: from molecular study to mechanobiology
Par Nathalie Sauvonnet (Pasteur)
Le 19 Mars 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
Shigella is an enteroinvasive bacterium that induces human bacillary dysentery. The delivery of 30 bacterial effectors inside host cells allows the bacteria to invade colon epithelial cells, lyse the ...
Calcium dynamics in neurons, extreme statistics and role of redundancy in molecular transduction
Par David Holcman (ENS/IBENS)
Le 12 Mars 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
Calcium plays a critical role in several synaptic transduction pathways. We report and discuss here fast calcium transients and how they are possible in dendritic spines. The talk will discuss fast ...
Active sieving : from flapping nano-doors to vibrating nanotubes
Par Sophie Marbach (LPS/ENS)
Le 5 Mars 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
Filtering specific molecules is a challenge faced for several vital needs: from biomedical applications like dialysis to the intensive production of clean water. The domain has been boosted over the ...
Exclusion, congestion, and the evolution of collective action
Par Jorge Peña (IAST, Toulouse)
Le 26 Février 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
Collective action occurs when individuals work together to provide a collective good. Examples abound in the social and natural sciences: humans collectively build houses, roads, and walls; lions work...
Understanding and steering microbial ecosystems for environmental biotechnologies: how does energy shape microbial community patterns?
Par Théodore Bouchez (Irstea)
Le 19 Février 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
Microbes are the most abundant living entities on earth and are key engines that drive earth's biogeochemical cycles. I will first briefly illustrate some of our research activities for better ...
Impact of gut microbiota on adult brain plasticity
Par Gabriel Lepousez (Institut Pasteur)
Le 12 Février 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33
New neurons are continuously generated in only a few areas of the adult mammalian brain--the olfactory bulb and the dentate gyrus--where they integrate into already functioning circuitry. In these ...

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