Optical Trapping in zebrafish Par Itia Favre Bulle (The University of Queensland, Australia) Le 25 Juin 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 This talk will give you an overview of the use of Optical Tweezers in biology, and more specifically in zebrafish and its vestibular system. Otoliths, or ear-stones, play an important role in ...

Quantitative cell biology patchwork: studies of cell volume regulation, dynamics and mechanics of the cell cortex, deformation of the cell nucleus and cell migration Par Matthieu Piel (Institut Curie) Le 18 Juin 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Quantitative cell biology patchwork: studies of cell volume regulation, dynamics and mechanics of the cell cortex, deformation of the cell nucleus and cell migration ...

Mobilité de Saffman-Delbrück et particules colloidales en phase lamellaire Par Jean-Baptiste Fournier (MSC, Paris-Diderot) Le 11 Juin 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Dans une première partie, je discuterai comment obtenir de façon approchée mais simple la loi de Saffman-Delbrück, c'est-à-dire la mobilité (vitesse / force ...

Séminaire interne Par Wafa Ben Youssef / Iaroslava Golovkova Le 4 Juin 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 TBA

Understanding Molecular Mechanisms of Biological Error Correction Par Anatoly B. Kolomeisky (Rice University) Le 28 Mai 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 One of the most fascinating features of biological systems is the ability to sustain an extraordinary high accuracy of all major cellular processes despite the stochastic nature of underlying chemical...

What can we learn from experimental fitness landscapes? Par Claudia Bank (Gulbenkian Institute) Le 23 Mai 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Fitness landscapes, which map genotypes or phenotypes to fitness, have developed from a theoretical metaphor into a popular subject of experimental study. The quantification of the shape of fitness ...

AG Par Jean Perrin Le 21 Mai 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 AG

Evolutionary heritage is a predictor of signaling interaction in bacterial two-component regulatory systems Par Mohamed Barakat, Philippe Ortet (CEA Cadarache) Le 14 Mai 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Two-component systems (TCSs) are virtually ubiquitous signaling pathways, which typically comprise a histidine kinase (HK) that monitors an external signal and a response regulator (RR) that ...

Organogénèse Physique de l'intestin Par Nicolas Chevalier (MSC) Le 7 Mai 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 L’intestin est une pompe et un réacteur biochimique. Sa longueur (7 m chez l’adulte) garantit une surface  d’absorption importante des nutriments et permet de ...

Modeling gas, fluid, and particle transport in the lung airway system: the curse of scales Par Marcel Filoche (PMC/Polytechnique) Le 16 Avril 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 The pulmonary airway system is a highly hierarchical tree-like 3D network in charge of transferring oxygen from the upper airways down to the alveolar region where the gas exchange occurs between ...

C. albicans: invasive lifestyle on a chip Par Catherine Villard (Institut Curie) Le 9 Avril 2019 à 12h00 - Salle de séminaires 5ème étage, Tour 32-33 Fungi are ubiquitous in our environment. They are part of the so-called “rare biosphere” of the human microbiota, representing less than 0.1% of the microbiome in healthy individuals. ...

3-D Optical imaging of tissue dynamics: From label-free characterization of tissues to sensory-motor integration in the spinal cord Par Olivier Thouvenin Le 2 Avril 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Even though biological tissues are highly dynamic at many different scales, traditional optical microscopes can often enable to track only a portion of them. While the optical diffraction ...

Hierarchy and extremes in selections from pools of randomized proteins Par Clément Nizak (ESPCI) Le 26 Mars 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Variation and selection are the core principles of Darwinian evolution, but quantitatively relating the diversity of a population to its capacity to respond to selection is challenging. Here, we ...

How the enteric pathogen Shigella invades and destroys the gut: from molecular study to mechanobiology Par Nathalie Sauvonnet (Pasteur) Le 19 Mars 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Shigella is an enteroinvasive bacterium that induces human bacillary dysentery. The delivery of 30 bacterial effectors inside host cells allows the bacteria to invade colon epithelial cells, lyse the ...

Calcium dynamics in neurons, extreme statistics and role of redundancy in molecular transduction Par David Holcman (ENS/IBENS) Le 12 Mars 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Calcium plays a critical role in several synaptic transduction pathways. We report and discuss here fast calcium transients and how they are possible in dendritic spines. The talk will discuss fast ...

Active sieving : from flapping nano-doors to vibrating nanotubes Par Sophie Marbach (LPS/ENS) Le 5 Mars 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Filtering specific molecules is a challenge faced for several vital needs: from biomedical applications like dialysis to the intensive production of clean water. The domain has been boosted over the ...

Exclusion, congestion, and the evolution of collective action Par Jorge Peña (IAST, Toulouse) Le 26 Février 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Collective action occurs when individuals work together to provide a collective good. Examples abound in the social and natural sciences: humans collectively build houses, roads, and walls; lions work...

Understanding and steering microbial ecosystems for environmental biotechnologies: how does energy shape microbial community patterns? Par Théodore Bouchez (Irstea) Le 19 Février 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Microbes are the most abundant living entities on earth and are key engines that drive earth's biogeochemical cycles. I will first briefly illustrate some of our research activities for better ...

Impact of gut microbiota on adult brain plasticity Par Gabriel Lepousez (Institut Pasteur) Le 12 Février 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 New neurons are continuously generated in only a few areas of the adult mammalian brain--the olfactory bulb and the dentate gyrus--where they integrate into already functioning circuitry. In these ...

Task engagement induces population-level behavioral representations in primary auditory cortex Par Yves Boubenec (Département d'études cognitives, ENS) Le 5 Février 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Primary sensory cortices are classically considered to extract and represent stimulus features, while association and higher-order areas are thought to carry information about stimulus meaning. Here ...

Learning to soar using atmospheric thermals. Par Jérôme Wong Ng (Institut Pasteur) Le 29 Janvier 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 In a similar way to bacteria that have to navigate in their environment, soaring birds try to minimize their effort by finding and exploiting ascending currents. However the environment is highly ...

Spying on cells with glowing chemical-genetic hybrids Par Arnaud Gautier (ENS Chimie) Le 22 Janvier 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Deciphering the complex mechanisms controlling cells and organisms requires effective imaging systems and fluorescent probes to observe and quantify biomolecules in real time with high ...

Antigenic evolution of viruses in host populations Par Igor Rouzine (Sorbonne Université - LCQB) Le 15 Janvier 2019 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 To escape immune recognition in previously infected hosts, viruses evolve genetically in immunologically important regions. The host’s immune system responds by generating new memory cells ...

AG Par LJP Le 11 Décembre 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 AG

Seminaire Interne Par Anis Senoussi / Ananyo Maitra Le 27 Novembre 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 TBA

Insect navigation: lessons from walking ants and crawling larvae Par Antoine Wystrach (Centre de Recherches sur la Cognition Animale, Toulouse) Le 20 Novembre 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 The remarkable navigational abilities of insects are proof that small brains can produce exquisitely efficient, robust navigation in complex environments. We will see here how such behaviours can ...

Understanding spatiotemporal stoichiometry of proteins in living cells / A global view on HIV-1 fusion Par Sergi Padilla / Luis Alvarez (Oxford) Le 14 Novembre 2018 à 14h00 - Salle de séminaires 5ème étage, Tour 32-33 Number and Brightness : from theory to practice in understanding spatiotemporal stoichiometry of proteins in living cells - Luis Alvarez The study of protein spatiotemporal time resolved dynamics in ...

DNA microgels and microdroplets toward artificial cell-like systems Par Masahiro Takinoue (Tokyo Institute of Technology) Le 13 Novembre 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 In recent years, the study of DNA hydrogels has been actively continued in the wide range of research fields from biophysical basic science to biological applications. However, the behaviors of DNA ...

A sneak peak with light into opaque materials Par Sylvain Gigan (LKB) Le 6 Novembre 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Complex heterogeneous materials, that scatter light in a highly complex way, present a huge challenge for imaging (think of seeing inside or through milk or biological tissues) and a very interesting ...

Illuminating the regulation of bacterial DNA repair and mutagenesis using single-molecule and single-cell microscopy Par Stephan Uphoff (Oxford) Le 16 Octobre 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Evolutionary processes are driven by diverse molecular mechanisms that act in the creation and prevention of mutations. It remains unclear how these mechanisms are regulated because limitations of ...

Active depinning of bacterial droplets: The collective surfing of Bacillus subtilis Par Adrian Daerr (MSC, Univ Paris Diderot) Le 9 Octobre 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 How systems are endowed with migration capacity is a fascinating question with implications ranging from the design of novel active systems to the control of microbial populations. Bacteria, which can...

L'impact potentiel des microorganismes sur la chimie et la physique des nuages Par Anne-Marie Delort (Institut de Chimie de Clermont-Ferrand) Le 2 Octobre 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Bien que les microorganismes aient été découverts par Pasteur dans l’air, ce n’est que récemment qu’ils ont fait l’objet d’études ...

Phage-bacteria interactions in the mouse gut Par Marianne De Paepe (Institut Micalis, INRA) Le 18 Septembre 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 While it is clear that bacteriophages, the viruses that infect bacteria, abound in all bacterial communities, their role in the ecology of these communities remains poorly understood. In particular, ...

Shapes and dynamics of lipid membrane systems: from pulsatile artificial vesicles to intracellular membrane structures Par Morgan Chabanon (UCSD) Le 11 Septembre 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Cellular lipid bilayers are found to display incredibly diverse shapes and dynamics, both at the plasma membrane and at membrane bound organelles. To understand the relationship between the complex ...

Yeast rockets, or how do growing microbial colonies generate their own propelling flow in liquids Par Severine Atis (Harvard) Le 7 Septembre 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Transport phenomena shape and constantly reorganize materials at every scale, influencing their dispersion, segregation and clustering. Range expansions coupled with fluid flows are of great ...

Self-organization of motors, bundlers and microtubules Par Thomas Surrey, The Francis Crick Institute, London Le 3 Septembre 2018 à 14h00 - Salle de séminaires 5ème étage, Tour 32-33 During cell division, the bipolar spindle self-assembles and segregates the genetic material of the cell. For this task, microtubules are arranged in space and time by motor proteins and ...

Collective behaviors of motile bacteria Par Victor Sourjik (Max Planck Institute for Terrestrial Microbiology, Marburg) Le 30 Août 2018 à 14h30 - Salle de séminaires 5ème étage, Tour 32-33 Bacterial motility and chemotaxis are typically viewed as single-cell behaviors, used by individual bacteria to identify conditions that are favorable for growth. For the well-studied model ...

Surfing Energy Landscapes in Self-Assembling Systems: From trapped states to fueled matter with programmable lifetimes Par Andreas Walther (Albert-Ludwigs-University Freiburg) Le 26 Juin 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Synthetic self-assembling systems have largely been developed with a focus on equilibrium structures. Such structures have become switchable by integration of responsive elements, which is the basis ...

DNA double strand break repair in single E. coli cells Par Meriem El Karoui (The University of Edimbourgh) Le 19 Juin 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 It has been shown in recent years that even genetically identical cells behave differently because many central processes involve molecules present in small numbers. The inherent randomness of ...

Functions promoting the rise and fall of bacterial biofilms Par Jean-Marc Ghigo (Institut Pasteur) Le 12 Juin 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Surface-attached bacterial communities (biofilms) are widespread and contribute to infections and biofouling in medical and industrial settings. The dense and highly heterogeneous biofilm environment ...

Understanding the coupling between nucleosome and transcription factor dynamics Par Michael Poirier Le 5 Juin 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 The physical organization of all eukaryotic genomes is evolutionarily conserved. Histone protein octamers repeatedly wrap genomic DNA into nucleosomes to form long chromatin fibers. Nucleosomes and ...

To move, or not to move, that is the evolutionary question: Evolution of growth and dispersal in bacterial populations. Par Maxime Deforet Le 30 Mai 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 I will present two projects demonstrating the interplay between growth and dispersal in evolutionary contexts. In the first one, I focus on the evolution of expanding populations, such as bacterial ...

Le treuil élastocapillaire en une et deux dimensions Par Sébastien Neukirch (Institut Jean le Rond d'Alembert) Le 15 Mai 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33     Nous parlerons d'élasto-capillarité, domaine mellant la déformation des structures élastiques et les forces de tension de surface. En effet, les forces ...

High-resolution mapping of bifurcations in nonlinear biochemical circuits Par Anthony Genot (LIMMS/U. Tokyo, Japan) Le 10 Avril 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 DNA has emerged in the past decades as a versatile and powerful polymer to build and program at the nanoscale. A rich library of devices has been built with DNA: origamis [1], biochemical neural ...

Phototaxis and texture perception Par Sophia Karpenko et Jean-Baptiste Tomazo (LJP) Le 27 Mars 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Phototaxis : a behavioral implementation & neural underpinnings. (Sophia)   In-mouth texture perception (Jean-Baptiste) Recent psychophysics based experimental investigations on both ...

Continuous model for water and electrolytes Par Hélène Berthoumieux (LPTMC, UPMC) Le 20 Mars 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Water plays an essential role as a solvent for a broad range of processes in nanometric confinement, for example conformational change of proteins or ion transport in biological channels. Modeling ...

Autocatalytic reaction fronts in disorder media Par Laurent Talon Le 14 Mars 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Autocatalytic reaction fronts between two reacting species, propagate as solitary waves. The coupling between autocatalytic reaction front and forced hydrodynamic flow may lead to stationary fronts ...

Dynamics and mechanical properties of actin cytoskeleton networks in vitro and in cellulo Par Olivia du Roure (ESPCI) Le 13 Février 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Actin is a protein which self-assembles into highly dynamic semi-flexible filaments organized, within the cells, in different kind of meshworks (bundles, crosslinked or dendritic networks). The ...

Evolution of antimicrobial resistance and Synthetic networks with cells Par Loïc Marrec and Marc Van Der Hofstadt Serrano (LJP, Internal seminar) Le 6 Février 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Loïc's talk Quantifying the impact of a periodic presence of antimicrobial on resistance evolution in ahomogeneous microbial population of fixed sizeAbstract:Antimicrobial resistance is a major ...

Hydrodynamics of bacteria Par Eric Lauga (Cambridge, UK) Le 30 Janvier 2018 à 11h00 - Salle de séminaires 5ème étage, Tour 32-33 Most motile bacteria are equipped with multiple helical flagella, slender appendages whose rotation in viscous fluids allow the cells to self-propel. We highlight in this talk three consequences of ...