Upcoming seminars

10 FEB

Protrusion-driven initiation of motility on a compliant substrate By Pierre Recho - Laboratoire Inter-disciplinaire de Physique, Université Grenoble Alpes, Saint-Martin-d'Heres February 10, 2026 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 The conditions under which biological cells switch from a static to a motile state are fundamental to the understanding of many healthy and pathological processes. In this talk, we consider a cell ...

17 FEB

Probing spatiotemporal electrochemical dynamics on single bacterial cells By Ashley Nord - Centre de Biologie Structurale, Montpellier February 17, 2026 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 Electrochemical gradients across biological membranes are fundamental to cellular bioenergetics. In bacteria, the proton motive force (PMF) drives critical functions such as ATP synthesis and ...

10 MAR

TBA By Julien Husson - LadHyX, CNRS, Ecole polytechnique, Institut polytechnique de Paris, Palaiseau, France March 10, 2026 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 TBA

24 MAR

TBA By Renaud Bastien - Centre de Recherches sur la Cognition Animale, Centre de Biologie Intégrative, CNRS, Université de Toulouse III – Paul Sabatier, Toulouse, France March 24, 2026 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 TBA

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Previous seminars

Single-cell imaging approaches to study cell division homeostasis By Gilles Charvin - Institut de physiologie et de chimie biologique, Strasbourg January 27, 2026 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 Cell division homeostasis is essential for long-term cell survival and for the ability of cells to adapt to fluctuating environments. Our work aims to understand how cells integrate internal and ...

A zebrafish model of an episodic movement disorder links telencephalic dysregulation with sensorimotor coordination By Owen Randlett - Université Claude Bernard Lyon 1, Lyon, France January 20, 2026 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 Our group is interested in how the brain controls and adapts movement. In this project, we take a disease-first approach, using human genetic disorders both as translational models and as entry points...

Machine learning for monitoring biodiversity at scale By Thijs van der Plas - AI group, Wageningen University & Research January 13, 2026 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 Nature conservation faces a growing paradox: while unprecedented volumes of biodiversity data are being collected, effective conservation action is increasingly constrained by the lack of detailed, ...

AI mini-symposium at LJP By AI mini-symposium at LJP December 16, 2025 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 Program here

The Countoscope: Quantifying Dynamics by Counting Particles in Boxes By Sophie Marbach - Laboratoire PHENIX, Sorbonne Université, Paris, France December 9, 2025 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 Quantifying the dynamics of particle suspensions is a widespread interest in soft matter. For instance, probing the motion of cells or larger organisms can help us understand biological behavior. When...

Beyond Hopfield networks for the modeling of neural computations By Alexis Dubreuil - Institut des Maladies Neurodégénératives, Univ. Bordeaux-CNRS, Bordeaux & LJP, Sorbonne Université, Paris November 25, 2025 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 How does the collective activity of neurons leads to the emergence of behavior ? Attractor neural networks, such as the Hopfield model, have been proposed to underlie various computations involved in ...

Not gently down the stream: flow induces amyloid bonding in environmental and pathological fungal biofilms By Peter Lipke - Brooklyn College, City University of New York, New York, USA - !!! UNUSUAL DATE !!! November 12, 2025 at 11:00AM - Salle de séminaire IBPS - C404 (Bat C 4e Etage) On the surface of fungal cells under shear stress, amyloid-like cross-β bonds cluster adhesins to make high avidity adhesive patches. The cross-b bonding is essential for formation of robust...

Modulating photobleaching and phototoxicity with near-infrared co-illumination in fluorescence microscopy By Lydia Robert - MICALIS - INRAE Jouy-en Josas & Agathe Espagne - Dept of Chemistry, ENS Paris November 4, 2025 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 Fluorescence microscopy is often limited by photobleaching, which fades fluorescent signals, and by phototoxicity, which damages living cells during imaging. Photobleaching is thought to involve the ...

Intrinsic fluctuations in arousal shape the dynamic organization of the mouse brain large-scale networks By Jean Charles Mariani - Istituto Italiano di Tecnologia, Genoa, Italy October 7, 2025 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 Despite decades of applications in both clinical and preclinical settings, the exact nature of large-scale functional connectivity (FC) and resting-state network (RSN) activity remains debated. It has...

Memory and environment sensing in active systems By Marc Besse, Laboratoire Jean Perrin, CNRS UMR 8237, Sorbonne Université, Paris September 30, 2025 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 Active systems, such as living cells, are traditionally modelled via self-propelled particles driven by internal forces. It is however often assumed that these internal forces do not depend on the ...

Evolution of error correction through a need for speed By Riccardo Ravasio - University of Chicago September 23, 2025 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 Kinetic proofreading is an error-correcting mechanism by which biology expends energy to avoid mistakes during processes like replication and translation. Proofreading is typically assumed to evolve ...

3D cell mounds at topological defects By Pascal Silberzan - Institut Curie, Centre de Recherche, CNRS UMR 168, Paris September 16, 2025 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 3D tissues that develop from a monolayer can take different forms: from folded monolayers -tubes or spheres - to bulk tridimensional tissues such as muscles, stratified epithelia, or epithelial ...

Organizing space through liquid-liquid phase separation of biomolecules By Audrey Cochard September 9, 2025 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 Liquid-liquid phase separation (LLPS) has emerged as a central principle of subcellular organization. While membraneless condensates composition and function are increasingly understood, how cells ...

From active particles to flexible, deformable, and motile superstructures : a new type of soft robot of robots By Hamid Kellay - Laboratoire Ondes et Matière d’Aquitaine (LOMA) - Université de Bordeaux - Talence June 24, 2025 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 We study assemblies of rodlike robots made motile through self-vibration. When confined by circular scaffolds, dilute assemblies of these rods act as a 2D gas of particles. Above a critical surface ...

Dynamical Properties of Dense Associative Memory By Kazushi Miruma June 17, 2025 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 The dense associative memory is one of the basic modern Hopfield networks and can store large numbers of memory patterns. This model stores given patterns as attractors in its dynamics. While the ...

Plant root growth in mechanically heterogeneous substrates By Evelyne Kolb - Laboratoire PMMH - ESPCI -Paris June 3, 2025 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 The interaction between plant roots and soils is an interdisciplinary issue that concerns many communities, from biophysics and agronomy to civil engineering and geophysics. The presence of zones of ...

Model of immunotherapy in microfluidic droplets By Charles Baroud - Physical Microfluidics & Bio-engineering - Institut Pasteur & Ecole Polytechnique May 13, 2025 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 In this seminar I will show the approach we have developed to study the interactions between cytotoxic T cells and cancer spheroids in microfluidic droplets. I will describe the original technical ...

Multicellular development and collective behavior in the closest living relatives of animals By Thibaut Brunet - Biologie cellulaire évolutive et évolution de la morphogenèse, Institut Pasteur, Paris May 6, 2025 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 The origin of animals from unicellular ancestors has been a key step in our evolutionary origins. However, the cellular and molecular basis of this transition remain incompletely understood.  In ...

Microenvironmental cues and immune cell migration By Hélène Moreau - Institut Curie, : Immunité et Cancer - Dynamique spatio-temporelle des cellules du système immunitaire April 8, 2025 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 Cell migration is a pivotal process in immunity. Indeed, appropriate immune responses (i.e. efficient but not detrimental to the host) rely on the coordinated actions of multiple cellular players. ...

Maximally informative low-resolution representations of proteins highlight key intermediate steps along the folding pathway By Roberto Menichetti - Physics Department, University of Trento - Italy April 1, 2025 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 Maximally informative low-resolution representations of proteins highlight key intermediate steps along the folding pathway Roberto Menichetti *1,2 1Physics Department, University of Trento, Via ...

Towards mature biofilms – Impact of physical triggers in the transition and outdifferentiation of gonococcal colonies By Marc Hennes March 31, 2025 at 11:00AM - Zoom Biofilm formation is a hallmark of prokaryotic lifestyle and is characterized by strong regulation and out-differentiation of subpopulations with distinct properties. During maturation, embedded ...

Microfluidic Flow Induced by Magnetically Actuated Microscopic Cilia By Charles Paul MOORE - Matière et Systèmes Complexes, Université Paris Cité, Paris March 25, 2025 at 11:00AM - Jean Perrin Laboratory - Jussieu Campus - Towers 22-32 - 4th floor. - Room 407 Lungs are lined with a thin layer of mucus which aids in clearing away foreign particulate. To remove this dirty mucus from the lung, bronchi are lined with cilia: small hair-like structures which ...

From structure to function in biology By Stéphane BIEDZINSKI - CIRB, Collège de France, Paris March 20, 2025 at 10:00AM - Jean Perrin Laboratory - Jussieu Campus - Towers 22-32 - 4th floor. - Room 407 In Biology, structure and function are tightly linked. When considering physical properties of a biological system this link might seem obvious but when it comes to connecting structure to a ...

Living organisms dealing with water surface physics By Ludovic JAMI - Laboratoire INPHYNI, Nice, France March 18, 2025 at 11:00AM - Jean Perrin Laboratory - Jussieu Campus - Towers 22-32 - 4th floor. - Room 407 My research focus on complex physics problems for the understanding of organisms' adaptation and the interactions with their environment. In my presentation, I will present briefly works on ...

Multi-modal learning methods for single-cell data integration By Laura CANTINI - Institut Pasteur - CNRS UMR 3738 - Paris March 11, 2025 at 11:00AM - Jean Perrin Laboratory - Jussieu Campus - Towers 22-32 - 4th floor. - Room 407 Single-cell RNA sequencing (scRNAseq) is revolutionizing biology and medicine. The possibility to assess cellular heterogeneity at a previously inaccessible resolution, has profoundly impacted our ...

Self-Patterned Materials: From droplet emulsions and photonic foams to arrays of artificial cells on a chip By Joshua Ricouvier - Chemical and Biological Physics Department, Weizmann Institute of Science, Israel March 6, 2025 at 10:00AM - On Zoom During my PhD at the Microfluidics Laboratory (P. Tabeling, MMN, ESPCI Paris), I focused on the fabrication of disordered photonic materials. Bidisperse emulsions self-assemble on a chip to create ...

Understanding plants through motions By Mathieu RIVIERE - Laboratoire IUSTI, Aix-Marseille Université, France March 4, 2025 at 11:00AM - Jean Perrin Laboratory - Jussieu Campus - Towers 22-32 - 4th floor. - Room 407 While plants are sessile organisms, they display an extraordinary variety of movements. The interest of these is two-fold: (i) they rely on a rich diversity of physical mechanisms and (ii) they occur ...

Dynamics of motile bacterial suspensions: reaction to oxygen and interaction with passive particles By Julien BOUVARD - Living Systems Institute, University of Exeter, UK February 11, 2025 at 11:00AM - Jean Perrin Laboratory - Jussieu Campus - Towers 22-32 - 4th floor. - Room 407 The swimming motion of bacteria has recently seen an increasing interest from physicists, utilizing the recent progresses in microscopy and the development of microfluidics to study this ...

Mechanics of living systems: pressing for answers By Valentin LAPLAUD - Ladhyx, Ecole Polytechnique, France February 4, 2025 at 11:00AM - Jean Perrin Laboratory - Jussieu Campus - Cassan Bar - Building C - 4th floor - Room C404 In this talk I will present the two experimental systems that I have develloped during my PhD and postdoc : a magnetic pincher to probe the cortex of living animal cells and a microfluidic chip to ...

Development of physiologically-relevant microvessels for tissue engineering: when mechanics guides vessel formation By Mathieu Hautefeuille - IBPS - Sorbonne-Université - Developmental Biology and Microphysiological Systems January 28, 2025 at 11:00AM - Jean Perrin Laboratory - Jussieu Campus - Towers 22-32 - 4th floor. - Room 407 In this seminar, I will present the past and current work of my team at IBPS, aiming at constructing perfusable microvessels to develop physiologically-relevant tissue microenvironments on ...

Towards emulsion-based functional materials: from stimulable polymer capsules to biomimetic programmable colloidal assemblies By Lucas SIXDENIER - Dept. of Physics, New York University, New York, USA January 27, 2025 at 04:00PM - On Zoom Microemulsions, i.e. dispersions of liquid droplets in another liquid in which they are not soluble, are versatile platforms for the design of functional soft materials, such as ...

Forty years of Boltzmann machines and counting By Rémi Monasson - LPENS January 21, 2025 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 Botlzmann machines were invented 40 years ago and awarded the Nobel Prize in Physics last October. The talk will review the basic principles of these machines, and two recent developments we have done...

How does a bacterial adhesin make up its MinD? By Nicolas DESPRAT - Laboratoire de Physique de l'ENS - Paris January 14, 2025 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 Surface proteins are essential components of bacteria-environment interactions. Akin to their cytoplasmic counterparts, polar localization of surface proteins is required in many contexts such as cell...

Flagella-like beating of actin bundles driven by self-organized myosin waves By Pascal MARTIN - Physique des Cellules et Cance - UMR 168, Institut Curie, Paris December 17, 2024 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 Wave-like beating of eukaryotic cilia and flagella - threadlike protrusions found in many cells and microorganisms - is a classic example of spontaneous mechanical oscillations in biology. This type ...

Internal seminar. By Romain LEROUX - Frédéric JOUBERT December 10, 2024 at 11:00AM - 4th floor seminar room - LJP - Tower 22-23 Active-matter droplets: patterns of an active filament by Romain Leroux Known as the cytoskeleton, networks of active biopolymers dynamically shape the cell membrane. Described by active ...

Fluctuations in dense active matter and applications to epithelial cell movements By Yann-Edwin KETA (Lorentz Institute for Theoretical Physics, Leiden University, Netherlands) December 2, 2024 at 02:00PM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 Active matter is an umbrella term which applies to a broad range of living and synthetic systems, composed of individual units each capable of consuming energy to perform motion, hence driving the ...

Non Equilibrium Transitions in a Template Copying Ensemble and from noisy cell size control to population growth By Arthur GENTHON November 26, 2024 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 Part 1: Non Equilibrium Transitions in a Template Copying Ensemble The fuel-driven process of replication in living systems generates distributions of copied entities with varying degrees of ...

Bacterial growth under confinement requires transcriptional adaptation to resist metabolite-induced turgor pressure build-up By Daria Bonazzi November 19, 2024 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 Bacterial proliferation often occurs in confined spaces, during biofilm formation, within hostcells, or in specific niches during infection, creating mechanical constraints. We investigated how ...

Prediction of neural activity in connectome-constrained recurrent networks By Manuel Beiran Amigo, Center for Theoretical Neuroscience, Columbia University, NY November 12, 2024 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 Establishing links between the connectivity of large neural networks and their emergent function is a major goal of neuroscience. In this talk, I will explain a theory of connectome-constrained ...

Internal seminar. By Léo Régnier and Elie Wandersman November 5, 2024 at 11:00AM - 4th floor seminar room - LJP - Tower 22-23 ***************************************************************** Random Walks Exploration and Starving, Léo Régnier   How long does it take for a tracer to reach a position ...

Osmotic control of nuclear size and the N/C ratio in fission yeast By Joël LEMIERE, Department of Cell and Tissue Biology, University of California, San Francisco October 22, 2024 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 The size of the nucleus scales robustly with cell size so that the nuclear-to-cell volume ratio (N/C ratio) is typically maintained as a constant in many cell types. Previous studies show that the N/C...

Newcomers' seminar. By TBA October 8, 2024 at 11:00AM - 4th floor seminar room - LJP - Tower 22-23 TBA

Electrodiffusion models of synaptic potentials in dendritic spines By Thibault LAGACHE, Institut Pasteur – Department of Cell Biology & Infection – BioImage Analysis October 1, 2024 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 The biophysical properties of dendritic spines play a critical role in neuronal integration but are still poorly understood, due to experimental difficulties in accessing them. Spine biophysics has ...

Force sensing in plants with mechanosensitive channels By Jean-Marie FRACHISSE, Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), 91198, Gif-sur-Yvette, France September 24, 2024 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 Plants, like all living organisms, are subject to mechanical forces either from their environment or from within their own bodies. For example, when the root encounters obstacles in the soil, or when ...

Two problems in microfluidics inspired by biology By Gabriel AMSELEM - LadHyX - Ecole Polytechnique, Palaiseau September 17, 2024 at 11:00AM - Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 I will present two topics we are currently working on in the lab. The first one concerns fluidic networks, which are pervasive in all clades of biology, from the vasculature of animals and plants to ...

Internal seminar. By Internal Seminar: Leonardo Demarchi, Silvia Grigolon September 10, 2024 at 11:00AM - C404 seminar room, 4th floor, building C, IBPS Visuomotor control in virtually swimming fish, by Leonardo Demarchi Understanding how the brain dynamically regulates behavior in response to a changing environment remains a fundamental question in ...